CDC73 and CCDC155

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CDC73	CCDC155
Gene Name		cell division cycle 73	coiled-coil domain containing 155
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cdc73/Paf1 Complex	Chromosome, Telomeric Region Lateral Element Nuclear Outer Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Core Binding Protein Binding	Identical Protein Binding Dynein Complex Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Transcription, DNA-templated MRNA Polyadenylation Cell Cycle Negative Regulation Of Cell Proliferation Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of MRNA 3'-end Processing Protein Destabilization Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Cellular Response To Lipopolysaccharide Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Double-strand Break Repair Via Homologous Recombination Spermatogenesis Oogenesis Chromosome Localization To Nuclear Envelope Involved In Synapsis
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation Hedgehog 'on' state formation of the beta-catenin:TCF transactivating complex XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Hedgehog Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		30 interactors: ALAS1 ANXA6 CCDC155 CEP70 CTNNB1 DDAH2 FAF1 FSD2 GC GOLGA2 HAP1 HIST1H1C HSF2BP HSPA4 ITFG1 KCNH2 KIAA1549 KIDINS220 MCM3AP MTUS2 PITHD1 RNF20 RNF40 TCEA1 TCF4 TFCP2 TOMM20 TSGA10 VPS37B WWC1	70 interactors: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 C17orf62 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LENG1 LHFPL5 MALL MARCH2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250
Entrez ID		79577	147872
HPRD ID		09581	08134
Ensembl ID		ENSG00000134371	ENSG00000161609
Uniprot IDs		Q6P1J9	Q8N6L0
PDB IDs
Enriched GO Terms of Interacting Partners?		Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2B Ubiquitination Cellular Localization Positive Regulation Of Glycoprotein Biosynthetic Process Establishment Of Localization In Cell Genitalia Morphogenesis Positive Regulation Of Glycoprotein Metabolic Process Organelle Organization Histone Monoubiquitination Regulation Of Glycoprotein Biosynthetic Process Establishment Of Protein Localization To Organelle Protein Localization Chromosome Organization Histone Ubiquitination Protein Import Positive Regulation Of Epithelial To Mesenchymal Transition Cellular Process Cytoplasmic Transport Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Histone Methylation Intracellular Transport Positive Regulation Of Neurogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Organ Growth Organelle Localization Transcription-coupled Nucleotide-excision Repair Regulation Of Oligodendrocyte Differentiation Protein Targeting Protein Monoubiquitination Myoblast Differentiation Regulation Of Intracellular Transport Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Chromosome Localization To Nuclear Envelope Involved In Synapsis Negative Regulation Of Potassium Ion Export Regulation Of Myelination Positive Regulation Of Intracellular Signal Transduction Skin Morphogenesis Vesicle Localization Regulation Of Histone Methylation Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Signal Transduction Positive Regulation Of Cell Development Genitalia Development Regulation Of Intracellular Signal Transduction Skin Development Regulation Of Epithelial To Mesenchymal Transition Protein Localization To Organelle Protein Transmembrane Transport	Membrane Fusion Organelle Fusion Vesicle Fusion Vesicle Fusion With Golgi Apparatus Negative Regulation Of Binding Membrane Organization Vesicle Organization Organelle Disassembly T Cell Chemotaxis SNARE Complex Assembly Negative Regulation Of Protein Binding Regulation Of Binding Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Vesicle-mediated Transport Regulation Of Cellular Component Organization Lymphocyte Chemotaxis Granulocyte Differentiation Endothelial Cell Proliferation T Cell Migration Transport Epithelial Cell Proliferation Low-density Lipoprotein Particle Clearance Embryo Development Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ER To Golgi Vesicle-mediated Transport Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Metanephros Development Mitochondrion Degradation Lymphocyte Migration Establishment Of Protein Localization Response To Linoleic Acid Positive Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Renal Albumin Absorption Negative Regulation Of Metanephric Mesenchymal Cell Migration Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Positive Regulation Of Metanephric Glomerular Visceral Epithelial Cell Development Detection Of Oxidative Stress Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Regulation Of Primitive Erythrocyte Differentiation Granulocyte Colony-stimulating Factor Signaling Pathway Molybdate Ion Transport
Tagcloud ?		1379delt affecting caucasian encoded fibroma hpt hyperparathyroidism hystologically instrumental jaw jt l460lfs mandible modelling moiety mtt ossifying parafibromin parathyroid partners proband pth relatives sanger sca silico terminus underlie vast
Tagcloud (Difference) ?		1379delt affecting caucasian encoded fibroma hpt hyperparathyroidism hystologically instrumental jaw jt l460lfs mandible modelling moiety mtt ossifying parafibromin parathyroid partners proband pth relatives sanger sca silico terminus underlie vast
Tagcloud (Intersection) ?