TFCP2 and PITPNM1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TFCP2	PITPNM1
Description		transcription factor CP2	phosphatidylinositol transfer protein membrane associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane Midbody Cleavage Furrow Golgi Cisterna Membrane Cell Body
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Calcium Ion Binding Protein Binding Phospholipid Transporter Activity Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Receptor Tyrosine Kinase Binding Phosphatidylcholine Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidic Acid Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Brain Development Phototransduction Protein Transport Phospholipid Transport Intermembrane Lipid Transfer
Pathways			Synthesis of PI
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12	5 interacting genes: CDK1 PLK1 PTK2B RHOA TFCP2
Entrez ID		7024	9600
HPRD ID		01790	07497
Ensembl ID		ENSG00000135457	ENSG00000110697
Uniprot IDs		Q12800	B2R787 O00562
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic	Microtubule Cytoskeleton Organization Involved In Mitosis Mitotic Nuclear Membrane Disassembly Golgi Organization Membrane Disassembly Nuclear Membrane Disassembly Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Midbody Protein Localization To Site Of Double-strand Break Regulation Of Organelle Assembly Mitotic G2 DNA Damage Checkpoint Signaling Negative Regulation Of Apoptotic Process Positive Regulation Of Lymphocyte Migration Spindle Microtubule Chromosome Condensation Positive Regulation Of Catalytic Activity Negative Regulation Of Programmed Cell Death Nuclear Membrane Organization Centrosome Cycle Cytoskeleton Organization Cell Cycle G2/M Phase Transition Protein Phosphorylation Mitotic G2/M Transition Checkpoint G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Modification Process Phosphorylation Mitotic Cytokinesis Regulation Of Lymphocyte Migration Mitotic DNA Damage Checkpoint Signaling Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Organelle Organization Mitotic Cleavage Furrow Formation Microtubule Cytoskeleton Organization Cell Division Pronuclear Fusion Microtubule Organizing Center Organization Neurotransmitter Receptor Regulator Activity Regulation Of Cytokinesis Regulation Of Primary Metabolic Process Regulation Of Catalytic Activity Aortic Valve Formation Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Organelle Organization Cytoskeleton-dependent Cytokinesis Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Regulation Of Cytoskeleton Organization
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