TFCP2 and PPP1R1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TFCP2	PPP1R1B
Description		transcription factor CP2	protein phosphatase 1 regulatory inhibitor subunit 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex	Nucleus Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Kinase Inhibitor Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Response To Amphetamine DNA-templated Transcription Signal Transduction Negative Regulation Of Female Receptivity Locomotory Behavior Visual Learning Intracellular Signal Transduction Response To Morphine Behavioral Response To Cocaine Cellular Response To Cocaine
Pathways			DARPP-32 events DARPP-32 events
Drugs
Diseases
GWAS			Asthma ( 31619474 31959851) Estimated glomerular filtration rate ( 31015462) Hematocrit ( 32888494) Hemoglobin ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12	9 interacting genes: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
Entrez ID		7024	84152
HPRD ID		01790	05097
Ensembl ID		ENSG00000135457	ENSG00000131771
Uniprot IDs		Q12800	B3KVQ9 Q9UD71
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic	Protein Kinase CK2 Complex Regulation Of Macroautophagy Neuromuscular Junction Protein Serine Kinase Activity Regulation Of Proteolysis Regulation Of Autophagy Regulation Of Protein Catabolic Process Protein Serine/threonine Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Regulation Of Cell Communication Regulation Of Signaling PcG Protein Complex Modulation Of Chemical Synaptic Transmission Protein Kinase Activity Macromolecule Catabolic Process Regulation Of Protein Export From Nucleus Regulation Of Proteasomal Protein Catabolic Process Glutamatergic Synapse Presynapse Hsp90 Protein Binding Kinase Activity Central Nervous System Neuron Development Protein Catabolic Process Double-strand Break Repair Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Glucose Metabolic Process Rhythmic Process Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synapse Organization Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Protein Catabolic Process At Presynapse, Modulating Synaptic Transmission Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Establishment Of Protein Localization Anatomical Structure Formation Involved In Morphogenesis Regulation Of Chromosome Separation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Macromolecule Metabolic Process Acetylcholine Receptor Activator Activity Regulation Of Cellular Component Organization Regulation Of Neurotransmitter Secretion Cerebral Cortex Development Negative Regulation Of Catabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Apoptotic Process Regulation Of Apoptotic Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?