TFCP2 and NHSL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TFCP2	NHSL2
Description		transcription factor CP2	NHS like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12	25 interacting genes: ABI3 ARID4B ATXN1 BTRC CLIC1 CTTN DYNLT1 GORASP2 HSF2BP INCA1 MAPK9 MTUS2 MYO15B NCK1 NCK2 PIH1D2 PLK1 PPP1R13B SH3RF1 SORBS3 TFCP2 TP53BP2 TRAF2 YWHAG YWHAH
Entrez ID		7024	340527
HPRD ID		01790	15001
Ensembl ID		ENSG00000135457	ENSG00000204131
Uniprot IDs		Q12800	A0A0J9YY72 Q5HYW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic	Cytoplasm Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Signaling Pathway Signaling Adaptor Activity Positive Regulation Of Protein Metabolic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Vesicle Membrane Signal Transduction Lamellipodium Organization Positive Regulation Of Translation In Response To Stress Positive Regulation Of Actin Filament Polymerization Signal Complex Assembly Regulation Of Biological Quality Positive Regulation Of Supramolecular Fiber Organization Substrate-dependent Cell Migration, Cell Extension Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Translational Initiation In Response To Stress Receptor Tyrosine Kinase Binding Intracellular Signal Transduction TORC1 Signaling Positive Regulation Of Programmed Cell Death Modification Of Postsynaptic Actin Cytoskeleton Negative Regulation Of PERK-mediated Unfolded Protein Response Positive Regulation Of Cytoskeleton Organization Cytosol Regulation Of Protein Metabolic Process Positive Regulation Of Protein-containing Complex Assembly Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of PERK-mediated Unfolded Protein Response TOR Signaling Insulin-like Growth Factor Receptor Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Signal Transduction Regulation Of Protein-containing Complex Assembly Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription By RNA Polymerase II Modification Of Postsynaptic Structure Modification Of Synaptic Structure Cytoskeletal Anchor Activity
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