TFCP2 and ZCCHC10

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TFCP2	ZCCHC10
Description		transcription factor CP2	zinc finger CCHC-type containing 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Eyebrow thickness ( 26926045)
Interacting Genes		73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12	55 interacting genes: ANKRD36B ARGLU1 BEND7 CAVIN1 CEP63 CEP70 COIL CTNNBL1 DAB1 DPPA2 DZIP3 EEF1A1 ELOA2 EPB41 FAM9B FRA10AC1 GKAP1 HMGXB4 IK KCTD6 KPNA3 LNX1 LUC7L2 MAB21L3 MEOX1 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 RPL22 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A
Entrez ID		7024	54819
HPRD ID		01790	15699
Ensembl ID		ENSG00000135457	ENSG00000155329
Uniprot IDs		Q12800	B3KVL5 B4DU89 D6R9G7 D6RHC2 G3XAM1 Q8TBK6
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic	RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Processing Spliceosomal Complex Nucleoplasm Nuclear Speck RNA Metabolic Process RNA Processing Protein-RNA Complex Assembly Nucleus Precatalytic Spliceosome Nucleic Acid Metabolic Process RNA Binding U2-type Prespliceosome Assembly Protein Binding Identical Protein Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process U1 SnRNP Cajal Body U12-type Spliceosomal Complex U2-type Spliceosomal Complex Protein-containing Complex Assembly Pre-mRNA 3'-splice Site Binding RS Domain Binding U4/U6 X U5 Tri-snRNP Complex Cytosol Protein-containing Complex Organization MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Small Nuclear Ribonucleoprotein Complex MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome
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