TFCP2 and MRPL11

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TFCP2	MRPL11
Gene Name		transcription factor CP2	mitochondrial ribosomal protein L11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus	Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter	Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		62 interactors: ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CASP8 CBX8 CCDC94 CDC73 COIL DNAJC27 DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM64A FANCL FARS2 FBXL18 GPANK1 HDAC1 HDAC2 IRAK1BP1 KIAA1598 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NFE4 NOM1 NPEPL1 PHF1 PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 SDCBP SIN3A STMN2 SUMO1 TCEA2 TDRD1 TRAPPC12 TSPAN12 UBP1 YY1 ZCCHC10 ZCCHC12	15 interactors: APP CAMK2B CAMK2D CRYAB FSD2 HMBOX1 HOMEZ JAKMIP2 KRT40 PNMA1 SLC16A9 TAX1BP1 TFCP2 THAP1 VPS52
Entrez ID		7024	65003
HPRD ID		01790	14739
Ensembl ID		ENSG00000135457	ENSG00000174547
Uniprot IDs		Q12800	Q9Y3B7
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Cellular Response To Stress Chromatin Modification Cellular Protein Metabolic Process Histone Modification Chromatin Organization Negative Regulation Of Gene Expression Cell Cycle Negative Regulation Of Cellular Metabolic Process Protein Metabolic Process Histone Deacetylation Regulation Of Gene Expression Chromosome Organization Regulation Of Metabolic Process Protein Deacetylation TRIF-dependent Toll-like Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Activation Of Innate Immune Response Metabolic Process Negative Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Regulation Of Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Cellular Protein Modification Process Negative Regulation Of RNA Biosynthetic Process Peptidyl-amino Acid Modification Toll-like Receptor 4 Signaling Pathway Anatomical Structure Development Anatomical Structure Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated	Regulation Of Cellular Response To Heat Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Immune Response Defense Response Cellular Response To Heat Innate Immune Response Inhibitory G-protein Coupled Receptor Phosphorylation Neuromuscular Process Controlling Balance Developmental Cell Growth Regulation Of Cell Cycle Regulation Of Synapse Structure Or Activity Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Activation Of Meiosis Involved In Egg Activation Embryonic Ectodermal Digestive Tract Development Response To Heat Response To Inorganic Substance Collateral Sprouting In Absence Of Injury Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Response To Abiotic Stimulus Peptidyl-serine Phosphorylation Regulation Of Cell Cycle Process Interferon-gamma-mediated Signaling Pathway Neuromuscular Process Regulation Of Generation Of L-type Calcium Current Activation Of Meiosis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Rac Protein Signal Transduction Regulation Of Histone Deacetylase Activity Cellular Response To Interferon-gamma Cell Growth Regulation Of RNA Metabolic Process Immune System Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Ectodermal Cell Differentiation Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Growth Response To Interferon-gamma Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Regulation Of Synaptic Transmission, Cholinergic
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