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CDC73 and FSD2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CDC73
FSD2
Gene Name
cell division cycle 73
fibronectin type III and SPRY domain containing 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cdc73/Paf1 Complex
Molecular Function
RNA Polymerase II Core Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Endodermal Cell Fate Commitment
Transcription, DNA-templated
MRNA Polyadenylation
Cell Cycle
Negative Regulation Of Cell Proliferation
Histone Monoubiquitination
Wnt Signaling Pathway
Stem Cell Maintenance
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of MRNA 3'-end Processing
Protein Destabilization
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Histone H2B Ubiquitination
Negative Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Fibroblast Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Cellular Response To Lipopolysaccharide
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
Hedgehog 'on' state
formation of the beta-catenin:TCF transactivating complex
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by Hedgehog
Signaling by Wnt
Signaling by WNT in cancer
Drugs
Diseases
GWAS
Subcutaneous adipose tissue (
22589738
)
Protein-Protein Interactions
30 interactors:
ALAS1
ANXA6
CCDC155
CEP70
CTNNB1
DDAH2
FAF1
FSD2
GC
GOLGA2
HAP1
HIST1H1C
HSF2BP
HSPA4
ITFG1
KCNH2
KIAA1549
KIDINS220
MCM3AP
MTUS2
PITHD1
RNF20
RNF40
TCEA1
TCF4
TFCP2
TOMM20
TSGA10
VPS37B
WWC1
42 interactors:
AES
AQP1
BEX2
BRD8
CBX8
CCDC112
CCHCR1
CDC73
CORO1A
ESD
FAM107A
FAM161A
FAM90A1
FMR1
IFT20
KANSL1
LATS1
LENG1
MRPL11
NDN
NGFRAP1
PBX3
PIK3R3
POLL
PPP1R18
PPP2R5D
PSMB4
SH2D4A
SPATC1L
TCEANC
ZBTB38
ZC2HC1C
ZMAT2
ZNF124
ZNF20
ZNF230
ZNF410
ZNF417
ZNF572
ZNF581
ZNF587
ZSCAN26
Entrez ID
79577
123722
HPRD ID
09581
17291
Ensembl ID
ENSG00000134371
ENSG00000186628
Uniprot IDs
Q6P1J9
A1L4K1
B7ZM02
B7ZM05
PDB IDs
Enriched GO Terms of Interacting Partners
?
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Histone H2B Ubiquitination
Cellular Localization
Positive Regulation Of Glycoprotein Biosynthetic Process
Establishment Of Localization In Cell
Genitalia Morphogenesis
Positive Regulation Of Glycoprotein Metabolic Process
Organelle Organization
Histone Monoubiquitination
Regulation Of Glycoprotein Biosynthetic Process
Establishment Of Protein Localization To Organelle
Protein Localization
Chromosome Organization
Histone Ubiquitination
Protein Import
Positive Regulation Of Epithelial To Mesenchymal Transition
Cellular Process
Cytoplasmic Transport
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Histone Methylation
Intracellular Transport
Positive Regulation Of Neurogenesis
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Organ Growth
Organelle Localization
Transcription-coupled Nucleotide-excision Repair
Regulation Of Oligodendrocyte Differentiation
Protein Targeting
Protein Monoubiquitination
Myoblast Differentiation
Regulation Of Intracellular Transport
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Chromosome Localization To Nuclear Envelope Involved In Synapsis
Negative Regulation Of Potassium Ion Export
Regulation Of Myelination
Positive Regulation Of Intracellular Signal Transduction
Skin Morphogenesis
Vesicle Localization
Regulation Of Histone Methylation
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Signal Transduction
Positive Regulation Of Cell Development
Genitalia Development
Regulation Of Intracellular Signal Transduction
Skin Development
Regulation Of Epithelial To Mesenchymal Transition
Protein Localization To Organelle
Protein Transmembrane Transport
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Regulation Of Metabolic Process
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Wnt Signaling Pathway
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Cellular Process
Neurotrophin Signaling Pathway
Regulation Of Canonical Wnt Signaling Pathway
Cellular Metabolic Process
Histone Ubiquitination
Negative Regulation Of Canonical Wnt Signaling Pathway
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Posterior Compartment Specification
Anterior Compartment Pattern Formation
Opsin Transport
Histone Modification
Histone H4 Acetylation
Regulation Of DNA-templated Transcription, Elongation
Negative Regulation Of Wnt Signaling Pathway
Carbon Dioxide Transmembrane Transport
Corticotropin Secretion
Early Endosome To Recycling Endosome Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Respiratory Gaseous Exchange
Negative Regulation Of Cellular Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Uropod Organization
Metanephric Proximal Convoluted Tubule Development
Nitric Oxide Transport
Cellular Response To Mercury Ion
Formaldehyde Catabolic Process
Tagcloud
?
1379delt
affecting
caucasian
encoded
fibroma
hpt
hyperparathyroidism
hystologically
instrumental
jaw
jt
l460lfs
mandible
modelling
moiety
mtt
ossifying
parafibromin
parathyroid
partners
proband
pth
relatives
sanger
sca
silico
terminus
underlie
vast
Tagcloud (Difference)
?
1379delt
affecting
caucasian
encoded
fibroma
hpt
hyperparathyroidism
hystologically
instrumental
jaw
jt
l460lfs
mandible
modelling
moiety
mtt
ossifying
parafibromin
parathyroid
partners
proband
pth
relatives
sanger
sca
silico
terminus
underlie
vast
Tagcloud (Intersection)
?