ASPSCR1 and ADAMTSL4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ASPSCR1	ADAMTSL4
Gene Name		alveolar soft part sarcoma chromosome region, candidate 1	ADAMTS-like 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Extrinsic Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen
	Molecular Function	Molecular_function Protein Binding	Protease Binding Metalloendopeptidase Activity Protein Binding
	Biological Process	Intracellular Protein Transport Biological_process Glucose Homeostasis Regulation Of Glucose Import Membrane Organization	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Translocation of GLUT4 to the plasma membrane	Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS			Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		11 interactors: ADAMTSL4 APP KRT31 KRTAP10-8 NEDD4 NOTCH2NL PHAX TACC3 TCF4 VCP VCPKMT	106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587
Entrez ID		79058	54507
HPRD ID		06947	18237
Ensembl ID		ENSG00000169696	ENSG00000143382
Uniprot IDs		Q9BZE9	F8WAD0 Q6UY14 Q9UFG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleocytoplasmic Transport Cytoplasmic Transport Cellular Localization Intracellular Transport Neuromuscular Junction Development Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Transmission Of Virus Development Involved In Symbiotic Interaction Protein Localization Regulation Of Intracellular Transport Regulation Of Synapse Structure Or Activity Forebrain Development Response To Abiotic Stimulus Establishment Of Localization In Cell SnRNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Metabolic Process Regulation Of Neuron Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Collateral Sprouting In Absence Of Injury Notch Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Maintenance Of DNA Repeat Elements Cellular Protein Localization Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Positive Regulation Of Cell Death Protein Transport Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Establishment Of Protein Localization Synapse Organization Regulation Of Protein Deubiquitination Progesterone Receptor Signaling Pathway Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Embryonic Hindgut Morphogenesis Astral Microtubule Organization Regulation Of Neurogenesis Regulation Of Cellular Response To Growth Factor Stimulus Embryonic Genitalia Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage	Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		17p 1p36 1q 1q13 1q21 4q21 7p 7q 8p 8q 8q11 9p cirrhotic etv1and ffpe fgfr3 gains hcc hccs maf nearby pathologically pter q23 q26 recql4 stac xp xq	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Difference) ?		17p 1p36 1q 1q13 1q21 4q21 7p 7q 8p 8q 8q11 9p cirrhotic etv1and ffpe fgfr3 gains hcc hccs maf nearby pathologically pter q23 q26 recql4 stac xp xq	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Intersection) ?