ASPSCR1 and TACC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ASPSCR1	TACC3
Description		ASPSCR1 tether for SLC2A4, UBX domain containing	transforming acidic coiled-coil containing protein 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Perinuclear Region Of Cytoplasm	Spindle Pole Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Cytoskeleton Centriolar Satellite Ciliary Basal Body Mitotic Spindle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Protein Modification Process Glucose Homeostasis Regulation Of D-glucose Import	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Nuclear Migration Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane	NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases		Alveolar soft part sarcoma
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Lung function (FVC) ( 30804560) Offspring birth weight ( 31043758) Waist-to-hip ratio adjusted for BMI ( 34021172)	Appendicular lean mass ( 33097823) Bladder cancer ( 20972438 24163127) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		17 interacting genes: ADAMTSL4 APP CLK2 INCA1 KRT31 KRTAP1-1 KRTAP10-8 NEDD4 NOTCH2NLA NSF PHAX TACC3 TCF4 UBC VCP VCPKMT WEE2-AS1	30 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 CATSPERT CCHCR1 CDC20B CDKL5 CIB3 CLIP4 DRC10 EIF3C GDF15 KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C
Entrez ID		79058	10460
HPRD ID		06947	05601
Ensembl ID		ENSG00000169696	ENSG00000013810
Uniprot IDs		Q9BZE9	A0A087WUE2 Q9Y6A5
PDB IDs		5IFS 5IFW 7OAT	5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?			Cytoplasm Aryl Hydrocarbon Receptor Binding Aryl Hydrocarbon Receptor Complex Microtubule-based Process Mitotic Centrosome Separation Centrosome Localization Axon Hillock Centrosome Separation
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