ASPSCR1 and NSF

Number of citations of the paper that reports this interaction (PubMedID 25078495)
48

Data Source:
BioGRID (pull down)

		ASPSCR1	NSF
Description		ASPSCR1 tether for SLC2A4, UBX domain containing	N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Lysosomal Membrane Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Dendritic Shaft GABA-ergic Synapse Postsynaptic Specialization, Intracellular Component
	Molecular Function	Protein Binding	SNARE Binding Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Syntaxin-1 Binding Protein Kinase Binding Syntaxin Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding Protein-containing Complex Binding Metal Ion Binding ATP-dependent Protein Disaggregase Activity
	Biological Process	Intracellular Protein Transport Positive Regulation Of Protein Modification Process Glucose Homeostasis Regulation Of D-glucose Import	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane	COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs			1-Ethyl-Pyrrolidine-2,5-Dione
Diseases		Alveolar soft part sarcoma
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Lung function (FVC) ( 30804560) Offspring birth weight ( 31043758) Waist-to-hip ratio adjusted for BMI ( 34021172)	Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (global PC1) ( 32198502) Cortical volume ( 32963231) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 21812969 19915575) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Refractive error ( 32231278) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)
Interacting Genes		17 interacting genes: ADAMTSL4 APP CLK2 INCA1 KRT31 KRTAP1-1 KRTAP10-8 NEDD4 NOTCH2NLA NSF PHAX TACC3 TCF4 UBC VCP VCPKMT WEE2-AS1	31 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FILNC1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 MEOX2 NAPA NAPG PLK2 PTPN9 RAMP3 RNF10 RPLP1 STX1A STX4 STX8 USO1 VAPA
Entrez ID		79058	4905
HPRD ID		06947	03380
Ensembl ID		ENSG00000169696	ENSG00000073969
Uniprot IDs		Q9BZE9	A0A384MTI6 P46459
PDB IDs		5IFS 5IFW 7OAT	6KZQ
Enriched GO Terms of Interacting Partners?			Membrane Fusion SNARE Complex Intracellular Protein Localization SNARE Binding Protein Transport Organelle Localization By Membrane Tethering Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Membrane Docking SNAP Receptor Activity Vesicle Fusion Establishment Of Protein Localization Chemical Synaptic Transmission Organelle Membrane Fusion Trans-synaptic Signaling Synaptic Signaling G Protein-coupled GABA Receptor Activity G Protein-coupled GABA Receptor Complex G Protein-coupled Receptor Heterodimeric Complex Organelle Fusion Intracellular Protein Transport Vesicle Docking Positive Regulation Of Synaptic Transmission Dendritic Spine Regulation Of Protein Localization To Cell Periphery GABA Receptor Complex Golgi Vesicle Transport Soluble NSF Attachment Protein Activity Regulation Of Protein Localization To Membrane Membrane Organization Negative Regulation Of Dopamine Secretion Vesicle Organization Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Modulation Of Chemical Synaptic Transmission Intracellular Transport Regulation Of Postsynaptic Membrane Potential Neuron-glial Cell Signaling Regulation Of Catecholamine Secretion Negative Regulation Of Synaptic Transmission Establishment Of Localization In Cell GABA Receptor Activity AMPA Glutamate Receptor Activity Postsynaptic Membrane Regulation Of Protein Localization To Plasma Membrane ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Synaptic Transmission, Glutamatergic Cell-cell Signaling Syntaxin Binding Endomembrane System
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?