ZNF24 and COPS6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNF24	COPS6
Gene Name		zinc finger protein 24	COP9 signalosome subunit 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Cytoplasm COP9 Signalosome Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Myelination Negative Regulation Of Transcription, DNA-templated	Cullin Deneddylation Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: APLP1 C14orf1 CCDC130 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G FANCA HAP1 HMGB1 KAT5 KIAA1377 LMO2 LRIF1 MID2 MZF1 PGBD1 PPP1CC RBM48 SCAND1 SEC62 SETDB1 SUMO1 TCAF1 TP53 TRIM25 UNC119 UTP14A ZBTB16 ZKSCAN8 ZNF165 ZNF174 ZNF396 ZNF446 ZNF483 ZNHIT3 ZSCAN21 ZSCAN32	84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24
Entrez ID		7572	10980
HPRD ID		01921	16735
Ensembl ID		ENSG00000172466	ENSG00000168090
Uniprot IDs		P17028	Q7L5N1
PDB IDs		1X6E 3LHR
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Base-excision Repair Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Viral Release From Host Cell DNA Repair Negative Regulation Of Viral Entry Into Host Cell Metabolic Process Regulation Of Viral Entry Into Host Cell Entrainment Of Circadian Clock By Photoperiod Regulation Of Viral Release From Host Cell Photoperiodism Entrainment Of Circadian Clock Protein Localization To Organelle Double-strand Break Repair Negative Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Negative Regulation Of Apoptotic Cell Clearance Cellular Response To DNA Damage Stimulus Cellular Response To Organic Substance Regulation Of Cellular Process	Cullin Deneddylation Protein Deneddylation Developmental Process Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Catalytic Activity Tissue Development Mitotic Cell Cycle Programmed Cell Death Apoptotic Signaling Pathway Response To Stress Cell Death Catabolic Process Death Regulation Of Cell Proliferation Mitotic Cell Cycle Process Cellular Response To Stress Response To Abiotic Stimulus G1/S Transition Of Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Phosphorylation Response To Organic Cyclic Compound Cell Cycle Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Organ Development Multicellular Organismal Development Epithelium Development Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death System Development Negative Regulation Of Cell Death Cellular Macromolecule Catabolic Process Response To Organic Substance Regulation Of Protein Kinase Activity Positive Regulation Of Cell Death
Tagcloud ?		18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf271 znf396 znf397	aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?		18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf271 znf396 znf397	aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?