ZNF24 and ZSCAN12

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ZNF24	ZSCAN12
Name		zinc finger protein 24	zinc finger and SCAN domain containing 12
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Myelination Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II
GWAS		No GWAS studies recorded	Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Brain morphology (MOSTest) ( 32665545 ) Chronic obstructive pulmonary disease ( 33909500 ) Fish- and plant-related diet ( 32066663 ) Lung cancer ( 28604730 ) Refractive error ( 32231278 ) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848 ) Sleep duration (short sleep) ( 30846698 ) Smoking initiation (ever regular vs never regular) ( 30679032 ) Squamous cell lung carcinoma ( 28604730 ) Subcortical volume (MOSTest) ( 32665545 )
Interacting Genes		47 interacting genes: APLP1 CEP126 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G ERG28 FAM161A FANCA HAP1 HMGB1 KAT5 LMO1 LMO2 LRIF1 MAP1LC3C MID2 NEK6 PPP1CC PRPF31 RBM48 SCAND1 SEC62 SETDB1 TCAF1 TP53 TRIM25 TRIM41 UBE2I UNC119 UTP14A YJU2B ZBTB16 ZGPAT ZKSCAN8 ZNF165 ZNF174 ZNF410 ZNF446 ZNF620 ZNHIT3 ZSCAN12 ZSCAN16 ZSCAN22 ZSCAN32	26 interacting genes: BICD2 CENPH CEP70 FAM161A KRTAP10-1 KRTAP10-8 LMNA MID2 MTUS2 PGBD1 RACK1 SCAND1 SRPK2 SSX2IP TFIP11 VCX VLDLR VPS26A ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF473 ZNF496 ZSCAN21 ZSCAN32
Entrez ID		7572	9753
HPRD ID		01921	15767
Ensembl ID		ENSG00000172466	ENSG00000158691
Uniprot IDs		P17028	A0A804HJ42 O43309
PDB IDs		1X6E 3LHR	Not available
GO Terms Enriched among Interactors		Zinc Ion Binding Nucleus Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Protein Binding Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding	None