FMNL1 and PRPF40A

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (pull down)
HPRD (two hybrid)

		FMNL1	PRPF40A
Gene Name		formin-like 1	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Cell Cortex Membrane Bleb Phagocytic Vesicle Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Membrane Nuclear Matrix Nuclear Speck
	Molecular Function	Molecular_function Protein Binding Profilin Binding GTPase Activating Protein Binding Rac GTPase Binding Actin Filament Binding	Protein Binding Poly(A) RNA Binding Proline-rich Region Binding
	Biological Process	Substrate-dependent Cell Migration Regulation Of Cell Shape Cortical Actin Cytoskeleton Organization Actin Filament Severing	MRNA Processing Cytoskeleton Organization Cell Cycle Regulation Of Cell Shape RNA Splicing Cell Migration Regulation Of Cytokinesis Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APP GAS7 HMG20A PFN1 PFN2 PRPF40A RAC1 TCERG1 XRCC6	120 interactors: ABI1 AKAP8L APBB1IP ARFGEF2 ASXL2 ATAD3A BAG6 BRD4 CAP2 CCT2 CCT4 CCT7 CDK12 CDK13 CHD3 CHERP CPSF6 CSNK2A1 CUL1 CYFIP1 CYFIP2 DAAM1 DDX46 DHX15 DHX8 DHX9 DIAPH1 ENAH ERG EVL FASLG FMN1 FMNL1 FMNL2 FMNL3 FN1 FNBP4 FRA10AC1 GAPDH HIPK1 HNRNPF HNRNPK HNRNPU HNRNPUL1 HSPG2 HTT IL1RAP KMT2B LARP7 LTBP3 MAP1LC3A MECP2 MMP11 NCKAP1L NKAP NONO PCBP2 PDCD7 PECAM1 PFKL PIAS1 PIAS3 PIAS4 PPIG PRKAR1A PSG5 PTPRF RBM39 RBMX2 RCC2 RLF RPL4 RPLP0 SDCBP SDCBP2 SDK1 SERPINB9 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SMAD4 SNIP1 SNRNP70 SON SRPK2 STIM2 U2AF1 U2AF2 U2SURP UBE2I UBE2K UBQLN1 UBQLN2 UBQLN4 UBR4 VASP VCL WAS WASF2 WASL WBP11 WBP4 WBP5 WIPF1 XRCC6 YBX1 YLPM1 YWHAG ZCCHC10 ZCCHC8 ZFHX3 ZHX1 ZNF341 ZNF451
Entrez ID		752	55660
HPRD ID		06876	10995
Ensembl ID		ENSG00000184922	ENSG00000196504
Uniprot IDs		O95466	O75400 Q05C41
PDB IDs			1UZC 1YWI 1YWJ 1ZR7 2CQN 2DYF 2KZG 2L5F 2L9V 2LKS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Ruffle Assembly Organelle Organization Cytoskeleton Organization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Hyperosmotic Response Platelet Activation Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Nervous System Development Positive Regulation Of ATPase Activity Actin Filament-based Process Regulation Of ATPase Activity Actin Filament Polymerization Generation Of Neurons Neurogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Development Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Transcription From RNA Polymerase II Promoter Platelet Degranulation Regulation Of Cellular Component Organization Negative Regulation Of Actin Filament Polymerization Regulation Of Actin Filament-based Process Positive Regulation Of Organelle Organization Blood Coagulation Actin Polymerization Or Depolymerization Hemostasis Negative Regulation Of Protein Polymerization Response To Osmotic Stress Regulation Of Cell Morphogenesis Regulation Of Metabolic Process Regulation Of Cell Projection Organization Protein Polymerization Regulation Of Cytoskeleton Organization Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Synaptic Growth At Neuromuscular Junction Regulation Of Body Fluid Levels	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Process Cellular Metabolic Process Cellular Component Assembly Actin Cytoskeleton Organization MRNA 3'-splice Site Recognition Actin Polymerization Or Depolymerization Actin Filament-based Process Cytoskeleton Organization RNA Biosynthetic Process Regulation Of Organelle Organization Transcription, DNA-templated Organelle Organization Regulation Of Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Component Organization CRD-mediated MRNA Stabilization Regulation Of Gene Expression Positive Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Nucleation Regulation Of Protein Metabolic Process Protein Sumoylation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of RNA Splicing Cell Differentiation Negative Regulation Of Cellular Metabolic Process Actin Filament Organization Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Multicellular Organismal Development Spliceosomal Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of RNA Metabolic Process Developmental Process
Tagcloud ?		actin biochemical cathepsin cation content depletion dispersal distinctly dramatic enlargement formin formins fragmentation golgi ill importantly integrity isoform lysosomal lysosomes maintain maintenance mannose member missorting nucleators phosphate relate	arginine arid3b arnt2 ascribed aspartate catabolism clmn defining deregulated ectopic fads1 focusing fth1 kpna2 lphn2 missense pard6b pde4c pias2 proline pygl regardless repressor reprogramming rhobtb2 seq transcriptome verifying xenobiotic
Tagcloud (Difference) ?		actin biochemical cathepsin cation content depletion dispersal distinctly dramatic enlargement formin formins fragmentation golgi ill importantly integrity isoform lysosomal lysosomes maintain maintenance mannose member missorting nucleators phosphate relate	arginine arid3b arnt2 ascribed aspartate catabolism clmn defining deregulated ectopic fads1 focusing fth1 kpna2 lphn2 missense pard6b pde4c pias2 proline pygl regardless repressor reprogramming rhobtb2 seq transcriptome verifying xenobiotic
Tagcloud (Intersection) ?