WRN and PARP1

  • Number of citations of the paper that reports this interaction (PMID 14734561)
  • 43
  • Data Source:
  • HPRD (in vivo)

WRN

PARP1

Gene Name Werner syndrome, RecQ helicase-like poly (ADP-ribose) polymerase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Exercise treadmill test traits ( 17903301)
Protein-Protein Interactions 26 interactors: ATM ATRX BLM CDKN2A FEN1 H2AFX MDC1 PARP1 PCNA POLB POLD2 POLR1C PRKAR1B PRKDC RAD51 RAD52 RAD54B RPA1 SUMO1 SUMO2 TERF2 TP53 VCP WRNIP1 XRCC5 XRCC6 84 interactors: APLF APTX ATM BCL2 BUB3 CASP1 CASP3 CASP7 CASP8 CD86 CDKN1A CENPA CENPB CREBBP CTSB CTSG E2F1 ERCC6 ERG FOXO1 GTF2F1 GZMB GZMM H2AFY HDAC1 HDAC3 HIST1H1A HIST1H1C HIST1H2BA HIST1H4A HIST1H4C HIST2H2AA3 HMGA1 HOXB7 HSPA2 KAT2B LIG3 LZTR1 MED14 MED6 MYBL2 NCL NCOA6 NEDD8 NFATC1 NFKB1 NPM1 NRF1 PARP2 PARP3 PCNA PIAS4 POLA1 POLA2 POLB POU2F1 PRKDC RARA RBM14 RELA RNF146 RPS3A RXRA SENP1 SENP3 SIRT1 SP1 SREK1 SUMO1 SUMO2 SUPT16H SWAP70 TCF4 TP53 TRIM29 UBE2I UHRF1 WRN XRCC1 XRCC5 XRCC6 ZBTB16 ZBTB9 ZNF423
Entrez ID 7486 142
HPRD ID 05212 01435
Ensembl ID ENSG00000165392 ENSG00000143799
Uniprot IDs Q14191 Q59F09 P09874
PDB IDs 2AXL 2DGZ 2E1E 2E1F 2FBT 2FBV 2FBX 2FBY 2FC0 3AAF 1UK0 1UK1 1WOK 2COK 2CR9 2CS2 2DMJ 2JVN 2L30 2L31 2RCW 2RD6 2RIQ 3GJW 3GN7 3L3L 3L3M 3OD8 3ODA 3ODC 3ODE 4AV1 4DQY 4GV7 4HHY 4HHZ 4L6S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cd71  commercially  concomitant  confirmation  diagnosing  embedded  erythroblasts  erythroid  erythroleukemia  hematological  immunocytochemistry  immunohistochemical  immunostaining  localized  marrow  missing  nearly  nuclei  paraffin  polyclonal  precursors  sections  strongest  terminus  tp53  truncated  werner  worthy  ws 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Difference) ?
cd71  commercially  concomitant  confirmation  diagnosing  embedded  erythroblasts  erythroid  erythroleukemia  hematological  immunocytochemistry  immunohistochemical  immunostaining  localized  marrow  missing  nearly  nuclei  paraffin  polyclonal  precursors  sections  strongest  terminus  tp53  truncated  werner  worthy  ws 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Intersection) ?