WRN and PRKDC

  • Number of citations of the paper that reports this interaction (PMID 11889123)
  • 45
  • Data Source:
  • HPRD (in vitro, in vivo)

WRN

PRKDC

Gene Name Werner syndrome, RecQ helicase-like protein kinase, DNA-activated, catalytic polypeptide
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Exercise treadmill test traits ( 17903301)
Protein-Protein Interactions 26 interactors: ATM ATRX BLM CDKN2A FEN1 H2AFX MDC1 PARP1 PCNA POLB POLD2 POLR1C PRKAR1B PRKDC RAD51 RAD52 RAD54B RPA1 SUMO1 SUMO2 TERF2 TP53 VCP WRNIP1 XRCC5 XRCC6 83 interactors: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CHEK1 CHEK2 CHUK CIB1 CTDP1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 ERG GSK3A GSK3B GZMB H2AFX HDAC3 HIST1H1A HIST1H1C HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11A NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R2 PPP6R3 PRKCD PTS RAD17 RBBP8 RNF144A RPA1 RPA2 SGOL1 SP1 SRF THRA THRB TP53 TREX1 UBC USF1 VPRBP WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ
Entrez ID 7486 5591
HPRD ID 05212 02941
Ensembl ID ENSG00000165392 ENSG00000253729
Uniprot IDs Q14191 Q59F09 P78527
PDB IDs 2AXL 2DGZ 2E1E 2E1F 2FBT 2FBV 2FBX 2FBY 2FC0 3AAF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cd71  commercially  concomitant  confirmation  diagnosing  embedded  erythroblasts  erythroid  erythroleukemia  hematological  immunocytochemistry  immunohistochemical  immunostaining  localized  marrow  missing  nearly  nuclei  paraffin  polyclonal  precursors  sections  strongest  terminus  tp53  truncated  werner  worthy  ws 
1ada  1p24  antiretroviral  atazanavir  atv  boosted  capacities  carriage  coating  depots  fa  folic  il2rg  loads  mirrored  nanoart  nanocrystals  nanoformulated  p407  parafollicular  paralleled  permit  pharmacodynamic  poloxamer  reconstituted  ritonavir  szj  tm1wjl  untargeted 
Tagcloud (Difference) ?
cd71  commercially  concomitant  confirmation  diagnosing  embedded  erythroblasts  erythroid  erythroleukemia  hematological  immunocytochemistry  immunohistochemical  immunostaining  localized  marrow  missing  nearly  nuclei  paraffin  polyclonal  precursors  sections  strongest  terminus  tp53  truncated  werner  worthy  ws 
1ada  1p24  antiretroviral  atazanavir  atv  boosted  capacities  carriage  coating  depots  fa  folic  il2rg  loads  mirrored  nanoart  nanocrystals  nanoformulated  p407  parafollicular  paralleled  permit  pharmacodynamic  poloxamer  reconstituted  ritonavir  szj  tm1wjl  untargeted 
Tagcloud (Intersection) ?