WRN and FEN1

  • Number of citations of the paper that reports this interaction (PMID 11598021)
  • 82
  • Data Source:
  • HPRD (in vivo, in vitro)

WRN

FEN1

Gene Name Werner syndrome, RecQ helicase-like flap structure-specific endonuclease 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Exercise treadmill test traits ( 17903301)
  • Metabolite levels ( 23378610)
  • Oleic acid (18:1n-9) plasma levels ( 23362303)
  • Palmitoleic acid (16:1n-7) plasma levels ( 23362303)
  • Phospholipid levels (plasma) ( 21829377)
  • Platelet counts ( 22139419)
  • Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions 26 interactors: ATM ATRX BLM CDKN2A FEN1 H2AFX MDC1 PARP1 PCNA POLB POLD2 POLR1C PRKAR1B PRKDC RAD51 RAD52 RAD54B RPA1 SUMO1 SUMO2 TERF2 TP53 VCP WRNIP1 XRCC5 XRCC6 15 interactors: APEX1 APP ARHGDIA BLM CCNA2 CDK1 CDK2 EEF1G EP300 GSK3B HNRNPA1 PCNA RAD1 TERF1 WRN
Entrez ID 7486 2237
HPRD ID 05212 02670
Ensembl ID ENSG00000165392 ENSG00000168496
Uniprot IDs Q14191 Q59F09 P39748 Q6FHX6
PDB IDs 2AXL 2DGZ 2E1E 2E1F 2FBT 2FBV 2FBX 2FBY 2FC0 3AAF 1U7B 1UL1 3Q8K 3Q8L 3Q8M 3UVU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cd71  commercially  concomitant  confirmation  diagnosing  embedded  erythroblasts  erythroid  erythroleukemia  hematological  immunocytochemistry  immunohistochemical  immunostaining  localized  marrow  missing  nearly  nuclei  paraffin  polyclonal  precursors  sections  strongest  terminus  tp53  truncated  werner  worthy  ws 
alka  alphaherpesvirus  analogy  backbone  cnjb  complexed  contrasts  crystallographic  emb  endonuclease  helical  helix  hhh  kinesin  kraut  kumar  motifs  nitrogens  nuclease  pelletier  pol  primer  sawaya  searches  shutoff  spt6  taq  virion  wilson 
Tagcloud (Difference) ?
cd71  commercially  concomitant  confirmation  diagnosing  embedded  erythroblasts  erythroid  erythroleukemia  hematological  immunocytochemistry  immunohistochemical  immunostaining  localized  marrow  missing  nearly  nuclei  paraffin  polyclonal  precursors  sections  strongest  terminus  tp53  truncated  werner  worthy  ws 
alka  alphaherpesvirus  analogy  backbone  cnjb  complexed  contrasts  crystallographic  emb  endonuclease  helical  helix  hhh  kinesin  kraut  kumar  motifs  nitrogens  nuclease  pelletier  pol  primer  sawaya  searches  shutoff  spt6  taq  virion  wilson 
Tagcloud (Intersection) ?