UBE2H and BYSL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		UBE2H	BYSL
Gene Name		ubiquitin-conjugating enzyme E2H	bystin-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Nucleolus Cytoplasm Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation Cell Adhesion Female Pregnancy Cell Proliferation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Red blood cell count ( 20139978)
Protein-Protein Interactions		57 interactors: BRAP BYSL CBLC CD99 DTX3 DTX3L DZIP3 EPS15 HDAC6 HIST2H2AA3 JADE1 LRSAM1 MARCH1 MARCH10 MARCH2 MARCH4 MARCH8 MKRN3 NEURL1 NHLRC1 POLL POLM RAG1 RELA RNF10 RNF103 RNF113B RNF114 RNF128 RNF133 RNF139 RNF144A RNF146 RNF166 RNF185 RNF186 RNF2 RNF34 RNF38 RNF4 RNF6 STAM2 TRAIP TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM28 TRIM36 TRIM37 TRIM5 TRIM56 UBA1 UBASH3B UBOX5 UBR2	65 interactors: AES AIMP2 APP BEND7 C1orf94 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 EMD EPS8 FAM9B FXR2 GMCL1 GOLGA2 HMBOX1 IKZF1 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LONRF1 LTV1 LZTS2 MID1 MID2 MIPOL1 MRFAP1L1 MTUS2 NECAB2 OLIG3 PDE4DIP PHC2 PNMA1 PNMA2 RALYL SMN2 SSX2IP STX11 TEKT1 THAP1 TNIP1 TRAF4 TRIM27 TRIM37 TRIM54 TRIP6 TRO TROAP UBE2H VPS37B ZBTB14 ZBTB8A ZFP64
Entrez ID		7328	705
HPRD ID		03052	04848
Ensembl ID		ENSG00000186591	ENSG00000112578
Uniprot IDs		A4D1L5 P62256	Q13895
PDB IDs		2Z5D
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Protein Polyubiquitination Protein Autoubiquitination Cellular Metabolic Process Negative Regulation Of Viral Release From Host Cell Protein Monoubiquitination Regulation Of Viral Release From Host Cell Metabolic Process Histone Ubiquitination Protein Catabolic Process Histone Monoubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Viral Process Protein K63-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Histone H2A Ubiquitination Histone H2A-K119 Monoubiquitination Regulation Of Viral Entry Into Host Cell Cellular Macromolecule Catabolic Process Cellular Process Negative Regulation Of Protein Metabolic Process Histone Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Viral Process Regulation Of ERBB Signaling Pathway Protein Trimerization Aggresome Assembly Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein K6-linked Ubiquitination Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Histone H2A Monoubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Chromatin Modification Negative Regulation Of Cellular Protein Metabolic Process Proteolysis Catabolic Process Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Negative Regulation Of Viral Entry Into Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Gene Expression Protein Localization To Microtubule RNA Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Cytoskeleton Organization RNA Biosynthetic Process Cell Adhesion Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Protein Complex Disassembly Negative Regulation Of Biosynthetic Process Dendritic Cell Migration Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Regulation Of Protein Depolymerization Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Organelle Organization Regulation Of Binding Regulation Of Metabolic Process Regulation Of Protein Complex Disassembly Cellular Macromolecule Biosynthetic Process Immune System Process Macromolecule Biosynthetic Process Negative Regulation Of Microtubule Depolymerization Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Neutrophil Differentiation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Memory T Cell Proliferation Regulation Of Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Developmental Process Microtubule-based Process Leukocyte Cell-cell Adhesion Negative Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 ctsf dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 rragd sdhd serpinf1 tbc1d1	c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49
Tagcloud (Difference) ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 ctsf dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 rragd sdhd serpinf1 tbc1d1	c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49
Tagcloud (Intersection) ?