BYSL and KRT8

Number of citations of the paper that reports this interaction (PMID 9560222)
17

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		BYSL	KRT8
Gene Name		bystin-like	keratin 8, type II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell	Nucleus Nucleoplasm Cytoplasm Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Structural Molecule Activity Protein Binding Protein Complex Binding Scaffold Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation Cell Adhesion Female Pregnancy Cell Proliferation	Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Red blood cell count ( 20139978)	Prostate cancer ( 21743057)
Protein-Protein Interactions		65 interactors: AES AIMP2 APP BEND7 C1orf94 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 EMD EPS8 FAM9B FXR2 GMCL1 GOLGA2 HMBOX1 IKZF1 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LONRF1 LTV1 LZTS2 MID1 MID2 MIPOL1 MRFAP1L1 MTUS2 NECAB2 OLIG3 PDE4DIP PHC2 PNMA1 PNMA2 RALYL SMN2 SSX2IP STX11 TEKT1 THAP1 TNIP1 TRAF4 TRIM27 TRIM37 TRIM54 TRIP6 TRO TROAP UBE2H VPS37B ZBTB14 ZBTB8A ZFP64	35 interactors: ANXA1 BYSL DEDD DMD EGFR FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT17 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO1 SUMO2 SUMO3 TCHP TFIP11 TROAP
Entrez ID		705	3856
HPRD ID		04848	01015
Ensembl ID		ENSG00000112578	ENSG00000170421
Uniprot IDs		Q13895	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression Protein Localization To Microtubule RNA Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Cytoskeleton Organization RNA Biosynthetic Process Cell Adhesion Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Protein Complex Disassembly Negative Regulation Of Biosynthetic Process Dendritic Cell Migration Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Regulation Of Protein Depolymerization Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Organelle Organization Regulation Of Binding Regulation Of Metabolic Process Regulation Of Protein Complex Disassembly Cellular Macromolecule Biosynthetic Process Immune System Process Macromolecule Biosynthetic Process Negative Regulation Of Microtubule Depolymerization Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Neutrophil Differentiation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Memory T Cell Proliferation Regulation Of Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Developmental Process Microtubule-based Process Leukocyte Cell-cell Adhesion Negative Regulation Of Transcription From RNA Polymerase II Promoter	Neurotrophin TRK Receptor Signaling Pathway MAPK Cascade Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Tissue Development Fc Receptor Signaling Pathway Signal Transduction By Phosphorylation Apoptotic Process Positive Regulation Of Protein Metabolic Process Programmed Cell Death Innate Immune Response Cell Death Death Immune Response-regulating Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Organic Substance Positive Regulation Of Transferase Activity MyD88-dependent Toll-like Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Lipid Response To Growth Factor Anatomical Structure Development Epidermal Growth Factor Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Defense Response Developmental Process Epithelium Development Response To Abiotic Stimulus Regulation Of Immune Response Positive Regulation Of Protein Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process
Tagcloud ?		c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49	ccna1 cdh1 circulatory code cohorts ctnnb1 differentially erbb2 explain favorable gata3 gli1 grouped hic1 highlighting interconnected ipa jun mki67 modulate notch1 predicts ptgs2 rassf1 regulators sfn transducers trigger triple
Tagcloud (Difference) ?		c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49	ccna1 cdh1 circulatory code cohorts ctnnb1 differentially erbb2 explain favorable gata3 gli1 grouped hic1 highlighting interconnected ipa jun mki67 modulate notch1 predicts ptgs2 rassf1 regulators sfn transducers trigger triple
Tagcloud (Intersection) ?