Wiki-Pi
About
Search
People
Updates
Search
RNF166 and UBE2K
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
RNF166
UBE2K
Description
ring finger protein 166
ubiquitin conjugating enzyme E2 K
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Cytoplasm
Cytosol
Filopodium Tip
Molecular Function
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Immune System Process
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Protein Ubiquitination
Innate Immune Response
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Peptidyl-threonine Phosphorylation
Free Ubiquitin Chain Polymerization
Protein Ubiquitination
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Interferon-beta
Type I Interferon-mediated Signaling Pathway
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Protein K48-linked Ubiquitination
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Negative regulators of DDX58/IFIH1 signaling
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Coffee consumption (
31046077
)
Hair color (
26926045
)
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Plasma amyloid beta peptide concentrations (ABx-40) (
24535457
)
Platelet count (
32888494
)
Interacting Genes
23 interacting genes:
CYLD
MAGEA1
MAGEC2
MKRN3
RNF41
SQSTM1
TRIM39
TRIM9
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2K
UBE2U
UBE2W
UBE2Z
USP2
XAF1
98 interacting genes:
AMFR
ANAPC11
BARD1
BFAR
BIRC7
BIRC8
BRCA1
CASP12
CBLC
CCNC
CDC6
CEBPA
DDI1
DIABLO
DTX3
DTX3L
DZIP3
EXOSC7
FZR1
HTT
ITCH
ITSN1
KRIT1
LRSAM1
MAP3K1
MARCHF3
MARCHF7
MDM2
MEOX2
MID1
MID2
MIPOL1
MKRN2
MKRN3
NEDD4L
NEDD8
NFKB1
NUB1
PAX6
PIAS4
PICK1
PJA1
PRKN
PRPF40A
PRRG4
RBCK1
RC3H2
REL
RING1
RLIM
RNF111
RNF114
RNF125
RNF138
RNF144A
RNF166
RNF167
RNF182
RNF183
RNF185
RNF2
RNF213
RNF31
RNF32
RNF4
RNF41
RNF5
SDCBP
SENP1
SH3RF1
SIAH1
SMURF1
TP53
TRAF7
TRAIP
TRIM13
TRIM2
TRIM27
TRIM3
TRIM31
TRIM34
TRIM35
TRIM39
TRIM43
TRIM5
TRIM50
TRIM6
TRIM63
TSN
UBA1
UBA5
UBE2I
UBOX5
UHRF2
USP1
WWP2
ZDHHC17
ZNF384
Entrez ID
115992
3093
HPRD ID
15260
04165
Ensembl ID
ENSG00000158717
ENSG00000078140
Uniprot IDs
Q96A37
B3KSH4
B4DIZ2
P61086
PDB IDs
1YLA
2O25
3E46
3F92
3K9O
3K9P
5DFL
6IF1
6JB6
6JB7
7MYF
7MYH
7OJX
Enriched GO Terms of Interacting Partners
?
Ubiquitin Conjugating Enzyme Activity
Post-translational Protein Modification
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Protein Modification Process
Protein Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Proteolysis
Modification-dependent Protein Catabolic Process
Macromolecule Catabolic Process
Ubiquitin-protein Transferase Activity
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Macromolecule Metabolic Process
Transferase Activity
Catabolic Process
Protein Monoubiquitination
ATP Binding
Protein Catabolic Process
Ubiquitin Protein Ligase Activity
Nucleotide Binding
Proteasomal Protein Catabolic Process
Ubiquitin Protein Ligase Binding
Protein K63-linked Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Nucleus
ISG15 Transferase Activity
Negative Regulation Of Metabolic Process
ISG15-protein Conjugation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Protein Autoubiquitination
Programmed Cell Death
Cell Death
Molecular Sequestering Activity
Nucleoplasm
Protein K6-linked Ubiquitination
Cytosol
Apoptotic Process
Response To Interferon-beta
Negative Regulation Of Interleukin-18-mediated Signaling Pathway
Met1-linked Polyubiquitin Deubiquitinase Activity
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Signal Transduction
Regulation Of Protein Ubiquitination
Negative Regulation Of Cell Communication
Ubiquitin Protein Ligase Activity
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Post-translational Protein Modification
Protein Modification Process
Ubiquitin-protein Transferase Activity
Protein Polyubiquitination
Transferase Activity
Zinc Ion Binding
Protein Metabolic Process
Macromolecule Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Protein Autoubiquitination
Metal Ion Binding
Macromolecule Catabolic Process
Proteolysis
Catabolic Process
Protein Catabolic Process
Protein K63-linked Ubiquitination
Proteasomal Protein Catabolic Process
Positive Regulation Of Catabolic Process
Cytoplasm
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Protein K48-linked Ubiquitination
Regulation Of Signaling
Regulation Of Cell Communication
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Stress
Identical Protein Binding
Protein K6-linked Ubiquitination
Regulation Of Metabolic Process
Positive Regulation Of Signal Transduction
Ubiquitin Ligase Complex
Innate Immune Response
Regulation Of Protein Catabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Suppression Of Viral Release By Host
Regulation Of Proteolysis
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
SUMO Transferase Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?