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SNRNP70 and SMAD5
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SNRNP70
SMAD5
Gene Name
small nuclear ribonucleoprotein 70kDa (U1)
SMAD family member 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
U1 SnRNP
Nuclear Speck
Intracellular
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Cytosol
Integral Component Of Membrane
Protein Complex
Molecular Function
Nucleotide Binding
RNA Binding
Protein Binding
Poly(A) RNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Receptor Signaling Protein Activity
Protein Binding
Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity
Ubiquitin Protein Ligase Binding
Metal Ion Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Regulation Of RNA Splicing
Positive Regulation Of MRNA Splicing, Via Spliceosome
Ureteric Bud Development
Mullerian Duct Regression
Osteoblast Fate Commitment
Transcription, DNA-templated
Protein Phosphorylation
Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
Germ Cell Development
Embryonic Pattern Specification
Erythrocyte Differentiation
BMP Signaling Pathway
Intracellular Signal Transduction
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription, DNA-templated
Cartilage Development
Cardiac Muscle Contraction
Bone Development
Cellular Response To Organic Cyclic Compound
Cellular Response To BMP Stimulus
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Signaling by BMP
Drugs
Diseases
GWAS
Protein-Protein Interactions
43 interactors:
APP
ARSF
CDKL3
CEP63
CHERP
CLK2
CRP
CSNK2A1
CTDP1
DDX17
GEMIN2
HNRNPA2B1
HTATSF1
IL32
IL7R
LRP1
MYC
NUDT21
PRKD2
PRMT5
PRPF40A
RASGRF1
RELA
RNF11
SCAF11
SHBG
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD5
SMAD9
SMURF2
SNRPC
SRPK1
SRPK2
SRSF1
SRSF10
SRSF2
TOP1
WBP4
ZRANB2
44 interactors:
ACVR1
ANKRD13A
BCAT1
BMP6
CHMP3
COPS5
CXXC5
EP300
FLNA
GDF6
HBG2
HGS
HOXA13
HOXD13
MBD1
MEN1
MTMR10
NEDD4
PLEKHO1
PNKP
PPIL4
PSMD11
PTPN12
RBM4
RYR2
SF3B1
SF3B3
SFPQ
SMAD1
SMAD4
SMURF1
SMURF2
SNRNP70
SNRPA
SOX5
SOX7
SUV39H1
SUV39H2
TOB1
U2AF2
UBA1
WWP1
ZEB2
ZNF8
Entrez ID
6625
4090
HPRD ID
01617
04381
Ensembl ID
ENSG00000104852
ENSG00000113658
Uniprot IDs
P08621
Q9UFS1
Q68DB7
Q99717
PDB IDs
2L5I
2L5J
3CW1
3PGW
Enriched GO Terms of Interacting Partners
?
RNA Processing
RNA Metabolic Process
Gene Expression
MRNA Processing
RNA Splicing
MRNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Nitrogen Compound Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Complex Assembly
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Cellular Macromolecular Complex Assembly
Mesonephros Development
Spliceosomal Complex Assembly
Regulation Of Gene Expression
Cellular Response To Growth Factor Stimulus
Cellular Metabolic Process
Response To Growth Factor
Kidney Epithelium Development
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Regulation Of RNA Splicing
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Cellular Component Assembly
Primary MiRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of Cell Differentiation
Regulation Of Metabolic Process
Regulation Of Cell Differentiation
Enzyme Linked Receptor Protein Signaling Pathway
BMP Signaling Pathway
Embryonic Pattern Specification
Anatomical Structure Development
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of MRNA Processing
BMP Signaling Pathway
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Gene Expression
Positive Regulation Of Gene Expression
RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Regulation Of Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Response To Transforming Growth Factor Beta
RNA Biosynthetic Process
Regulation Of Signal Transduction
Nucleobase-containing Compound Metabolic Process
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Tissue Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Ossification
Embryonic Morphogenesis
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Metabolic Process
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Tagcloud
?
1beta
affecting
alkaloid
anticancer
bcl
caspases
cdk1
compound
cytokines
cytotoxicity
g0
g1
inducing
k562
lamd
lamellarin
leukemia
marine
p27
panel
poorly
pronounced
smad3
stgc3
survivin
tgf
thinking
understood
way
Tagcloud (Difference)
?
1beta
affecting
alkaloid
anticancer
bcl
caspases
cdk1
compound
cytokines
cytotoxicity
g0
g1
inducing
k562
lamd
lamellarin
leukemia
marine
p27
panel
poorly
pronounced
smad3
stgc3
survivin
tgf
thinking
understood
way
Tagcloud (Intersection)
?