SNRNP70 and ARSF

Number of citations of the paper that reports this interaction (PMID 9685421)
13

Data Source:
HPRD (two hybrid, in vitro)

		SNRNP70	ARSF
Gene Name		small nuclear ribonucleoprotein 70kDa (U1)	arylsulfatase F
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck	Endoplasmic Reticulum Lumen Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Arylsulfatase Activity Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome	Sphingolipid Metabolic Process Glycosphingolipid Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism Post-translational protein modification The activation of arylsulfatases Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: APP ARSF CDKL3 CEP63 CHERP CLK2 CRP CSNK2A1 CTDP1 DDX17 GEMIN2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2	2 interactors: EP300 SNRNP70
Entrez ID		6625	416
HPRD ID		01617	02049
Ensembl ID		ENSG00000104852	ENSG00000062096
Uniprot IDs		P08621 Q9UFS1	P54793
PDB IDs		2L5I 2L5J 3CW1 3PGW
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Metabolic Process Gene Expression MRNA Processing RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Cellular Macromolecular Complex Assembly Mesonephros Development Spliceosomal Complex Assembly Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Cellular Metabolic Process Response To Growth Factor Kidney Epithelium Development Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of RNA Splicing Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Component Assembly Primary MiRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Differentiation Regulation Of Metabolic Process Regulation Of Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway BMP Signaling Pathway Embryonic Pattern Specification Anatomical Structure Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of MRNA Processing	Histone H2B Acetylation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Positive Regulation By Host Of Viral Transcription N-terminal Protein Amino Acid Acetylation Regulation Of Androgen Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of MRNA Splicing, Via Spliceosome N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Positive Regulation Of RNA Splicing Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Viral Transcription Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Protein Deacetylation Positive Regulation Of Gene Expression Histone H4 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Heat Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Binding Regulation Of Viral Transcription Positive Regulation Of Viral Process Positive Regulation Of Type I Interferon Production Somitogenesis Regulation Of MRNA Processing Protein Stabilization Endoplasmic Reticulum Unfolded Protein Response Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Somite Development Cellular Response To Hypoxia Cellular Response To Unfolded Protein Cellular Response To Decreased Oxygen Levels Regulation Of RNA Splicing ER-nucleus Signaling Pathway Regulation Of Type I Interferon Production Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Response To Heat Histone Acetylation Signal Transduction By P53 Class Mediator Segmentation G2/M Transition Of Mitotic Cell Cycle Internal Peptidyl-lysine Acetylation Positive Regulation Of Binding
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