SNRNP70 and CDKL3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SNRNP70	CDKL3
Gene Name		small nuclear ribonucleoprotein 70kDa (U1)	cyclin-dependent kinase-like 3
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: APP ARSF CDKL3 CEP63 CHERP CLK2 CRP CSNK2A1 CTDP1 DDX17 GEMIN2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2	17 interactors: APP ATG4A CCDC155 FXR2 GGA1 GOLGA2 KRTAP10-9 LZTS2 MDFI MTUS2 PIH1D3 SNRNP70 SRPK1 TRIM27 TTF2 ZBTB14 ZBTB8A
Entrez ID		6625	51265
HPRD ID		01617	09766
Ensembl ID		ENSG00000104852	ENSG00000006837
Uniprot IDs		P08621 Q9UFS1	B4DX41 E7ET86 Q8IVW4
PDB IDs		2L5I 2L5J 3CW1 3PGW	3ZDU
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Metabolic Process Gene Expression MRNA Processing RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Cellular Macromolecular Complex Assembly Mesonephros Development Spliceosomal Complex Assembly Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Cellular Metabolic Process Response To Growth Factor Kidney Epithelium Development Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of RNA Splicing Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Component Assembly Primary MiRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Differentiation Regulation Of Metabolic Process Regulation Of Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway BMP Signaling Pathway Embryonic Pattern Specification Anatomical Structure Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of MRNA Processing	MRNA Processing MRNA Metabolic Process Cellular Localization RNA Processing Regulation Of Binding Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Regulation Of Gene Expression Reproductive Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Viral Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus Sexual Reproduction RNA Splicing Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Pharynx Development Regulation Of MRNA Processing Negative Regulation Of Binding Intracellular Transport Regulation Of RNA Splicing RNA Metabolic Process Collateral Sprouting In Absence Of Injury Protein Delipidation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Reproduction Spermatogenesis Male Gamete Generation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Regulation Of Protein Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Viral Process Axon Choice Point Recognition Soft Palate Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Regulation Of Metabolic Process
Tagcloud ?			10a autophagic autophagosome autophagosomes bub1 catabolic csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pacsin1 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Difference) ?			10a autophagic autophagosome autophagosomes bub1 catabolic csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pacsin1 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Intersection) ?