Wiki-Pi
About
Search
People
Updates
Search
PFDN5 and TUBA1B
Number of citations of the paper that reports this interaction (PubMedID
35271311
)
106
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
PFDN5
TUBA1B
Description
prefoldin subunit 5
tubulin alpha 1b
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Prefoldin Complex
Protein-containing Complex
Intermediate Filament Cytoskeleton
Cytoplasm
Cytoskeleton
Microtubule
Cytoplasmic Microtubule
Cilium
Microtubule Cytoskeleton
Molecular Function
Amyloid-beta Binding
Transcription Corepressor Activity
Protein Binding
Unfolded Protein Binding
Nucleotide Binding
Double-stranded RNA Binding
GTPase Activity
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Hydrolase Activity
Ubiquitin Protein Ligase Binding
Biological Process
Regulation Of DNA-templated Transcription
Protein Folding
Negative Regulation Of DNA-templated Transcription
Retina Development In Camera-type Eye
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Amyloid Fibril Formation
RNA Polymerase I Assembly
RNA Polymerase II Core Complex Assembly
RNA Polymerase III Assembly
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule-based Process
Cytoskeleton-dependent Intracellular Transport
Cell Division
Cellular Response To Interleukin-4
Pathways
Prefoldin mediated transfer of substrate to CCT/TriC
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Recruitment of NuMA to mitotic centrosomes
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cargo trafficking to the periciliary membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
RHOH GTPase cycle
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
PKR-mediated signaling
Drugs
Epothilone D
Patupilone
CYT997
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS
Ambidextrousness (
32989287
)
Bipolar disorder (
31043756
)
Brain morphology (MOSTest) (
32665545
)
Left-handedness (
32989287
)
Left–right brain asymmetry (
33723403
)
Interacting Genes
113 interacting genes:
ABI2
ANKRD55
ATOSB
BCAS2
BCL6
BHLHE40
BRMS1
C10orf55
C10orf62
C22orf39
CALCOCO2
CCDC198
CEBPA
CIMIP1
CSPP1
DMRT3
DOK4
DOK5
EEIG1
ELK3
ESPNL
FAAP20
FAM110A
FAM221A
FAM222B
FAM90A1
GLRX3
GLYCTK
GPANK1
GSTO2
GUCD1
HAPLN2
HHEX
HOXB9
HOXC8
IKBKG
IKZF3
IL16
INCA1
IRX2
IRX6
ITSN1
KCTD9
KDM1A
KLHL38
KLHL42
LARP4
LNX1
MAP2K5
METTL21A
MISP
MRPL45
MYC
MYOT
MYOZ1
NEUROG2
NOXA1
NTAQ1
PATZ1
PAX9
PFDN6
PHF1
PHF24
PILRA
PITX1
PITX2
POGZ
PRKAB2
PRPF18
PRR35
PSMB4
PSMB8
PSME3
RIBC1
RIPPLY1
RSRC2
RUSC1
SAXO1
SAXO4
SCNM1
SDCBP
SHISA6
SLAIN1
SMAP1
SMG9
SNAI1
SNRNP25
SNRPB
SOHLH1
SPAG8
SPG21
SPMIP2
SPMIP4
SYCE1L
SYT17
TAF6L
TBX3
TCF19
TFG
TLE5
TP73
TRAPPC6A
TRIM28
TUBA1B
TUBA3C
VAX2
VEZF1
VGLL1
WDR25
WHR1
YPEL5
ZC2HC1C
ZNF148
39 interacting genes:
A2M
AGTRAP
EML4
EPN2
ESR1
FOXP1
FYN
GRM7
GZMM
HDAC6
ISG15
LINC00624
MAPT
MINK1
MTCL1
MYC
NFKBIA
OGT
PFDN5
PIK3R1
PSEN1
PTEN
PTP4A1
PTPRF
PXN
RNF26
RSPH1
RUNX1
SIAH1
SLX1B
SMAD2
SNAP91
SRPK2
SUMO2
TERT
TMEM253
TOM1L1
TUBG1
WEE2-AS1
Entrez ID
5204
10376
HPRD ID
05359
03960
Ensembl ID
ENSG00000123349
ENSG00000123416
Uniprot IDs
Q99471
P68363
PDB IDs
6NR8
6NR9
6NRB
6NRC
6NRD
7WU7
2E4H
5IJ0
5IJ9
5N5N
6E7B
6E7C
6I2I
6J4V
6J8O
6QUS
6QUY
6QVE
6QVJ
6S8L
7LXB
7M18
7M20
7PJF
7SJ7
7SJ8
7SJ9
7SJA
7Z6S
7ZCW
8T42
8U3Z
8V2J
8VA2
8VRJ
8VRK
8VT7
9BP6
Enriched GO Terms of Interacting Partners
?
Protein Binding
Negative Regulation Of Transcription By RNA Polymerase II
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Chromatin
Negative Regulation Of RNA Metabolic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
DNA-binding Transcription Factor Activity
Sequence-specific DNA Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Sequence-specific Double-stranded DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Binding
Positive Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of RNA Metabolic Process
Pattern Specification Process
MRF Binding
Regionalization
Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
E-box Binding
Axonemal A Tubule Inner Sheath
Negative Regulation Of Developmental Process
Beta-catenin Binding
Neuron Projection Organization
Negative Regulation Of Cellular Component Organization
Regulation Of Myeloid Cell Differentiation
Regulation Of Cellular Component Organization
Regulation Of Multicellular Organismal Development
Negative Regulation Of Multicellular Organismal Process
Regulation Of Developmental Process
Regulation Of Signal Transduction
Regulation Of Cell Development
Regulation Of Cell Communication
Regulation Of Signaling
Response To Stress
Regulation Of Anatomical Structure Morphogenesis
Negative Regulation Of Cell Differentiation
Regulation Of Protein Localization To Nucleus
Enzyme Binding
Negative Regulation Of Cell Development
Positive Regulation Of Protein Oligomerization
Negative Regulation Of Signal Transduction
Negative Regulation Of Protein Metabolic Process
Growth Factor Receptor Binding
Dendritic Spine Organization
Ubiquitin Protein Ligase Binding
Negative Regulation Of Myeloid Cell Differentiation
Organelle Organization
Clathrin Binding
Negative Regulation Of Hydrogen Peroxide Metabolic Process
Positive Regulation Of Protein Localization To Nucleus
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Neuron Projection Development
Positive Regulation Of Signaling
Regulation Of Multicellular Organismal Process
Neuron Projection
Regulation Of Cell Differentiation
Cellular Response To Reactive Oxygen Species
Cellular Response To Stress
Alpha-tubulin Binding
Tau Protein Binding
Postsynapse Organization
Positive Regulation Of Signal Transduction
Positive Regulation Of Cellular Component Organization
Regulation Of Protein Localization
Negative Regulation Of Gene Expression
Protein Modification Process
Regulation Of Establishment Of Protein Localization
Inclusion Body Assembly
Regulation Of Myeloid Leukocyte Differentiation
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?