ATP5F1C and ITIH2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5F1C	ITIH2
Description		ATP synthase F1 subunit gamma	inter-alpha-trypsin inhibitor heavy chain 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Proton-transporting ATP Synthase Complex	Extracellular Region Endoplasmic Reticulum Lumen Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Binding Protein Binding ATP Hydrolysis Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Hyaluronic Acid Binding Peptidase Inhibitor Activity
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Hyaluronan Metabolic Process
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE	Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Ovarian reserve ( 22116950)
Interacting Genes		30 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FAM120A FBXO7 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337	3 interacting genes: ATP5F1C FCER1A SPINT2
Entrez ID		509	3698
HPRD ID		00156	00890
Ensembl ID		ENSG00000165629	ENSG00000151655
Uniprot IDs		B4DL14 P36542 Q8TAS0	P19823
PDB IDs		8H9E 8H9F 8H9I 8H9J 8H9L 8H9M 8H9P 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Cell Cycle Angiostatin Binding Regulation Of Peptidyl-serine Phosphorylation Regulation Of Endothelial Cell Migration Regulation Of Cell Cycle Process Positive Regulation Of Cell Migration Proton-transporting Two-sector ATPase Complex Neuron Projection Organization Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Postsynapse Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Neuron Projection Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Long-term Synaptic Potentiation Proton Motive Force-driven Mitochondrial ATP Synthesis Estrous Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Transcription-coupled Nucleotide-excision Repair Cognition Regulation Of Mitotic Cell Cycle Proton Motive Force-driven ATP Synthesis Transmembrane Transporter Complex Negative Regulation Of Cell Population Proliferation Proton-transporting ATP Synthase Activity, Rotational Mechanism Regulation Of Cell Cycle G1/S Phase Transition Regulation Of MiRNA Transcription ATP Biosynthetic Process Protein Tyrosine Kinase Activator Activity Negative Regulation Of Cell Cycle Regulation Of MiRNA Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Serine-type Endopeptidase Inhibitor Activity Regulation Of Epithelial Cell Proliferation MHC Class I Protein Binding Ovulation Cycle Dendritic Spine Morphogenesis Nervous System Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Auditory Stimulus Proton-transporting ATP Synthase Complex Transcription Elongation Factor Complex Positive Regulation Of Peptidyl-serine Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process	High-affinity IgE Receptor Activity Type I Hypersensitivity Epithelial Cell Morphogenesis Involved In Placental Branching Eosinophil Degranulation IgE Binding Type 2 Immune Response Hypersensitivity
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