ATP5F1C and MED15

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5F1C	MED15
Description		ATP synthase F1 subunit gamma	mediator complex subunit 15
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Proton-transporting ATP Synthase Complex	Nucleus Nucleoplasm Cytoplasm Membrane Core Mediator Complex
	Molecular Function	RNA Binding Protein Binding ATP Hydrolysis Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Transcription Coregulator Activity Protein Binding
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Regulation Of DNA-templated Transcription Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS			Lung function (FEV1/FVC) ( 30061609)
Interacting Genes		30 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FAM120A FBXO7 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337	13 interacting genes: ATP5F1C ATXN1 CEBPA CTDP1 FHL3 MED25 MLLT6 PLSCR1 RELA SMAD2 SMAD3 TRIM11 UBC
Entrez ID		509	51586
HPRD ID		00156	12117
Ensembl ID		ENSG00000165629	ENSG00000099917
Uniprot IDs		B4DL14 P36542 Q8TAS0	B3KWF1 B7Z2H7 G3V1P5 Q6PKB8 Q96RN5
PDB IDs		8H9E 8H9F 8H9I 8H9J 8H9L 8H9M 8H9P 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3	2GUT 7EMF 7ENA 7ENC 7ENJ 7LBM 8GXQ 8GXS 8J9A 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Cell Cycle Angiostatin Binding Regulation Of Peptidyl-serine Phosphorylation Regulation Of Endothelial Cell Migration Regulation Of Cell Cycle Process Positive Regulation Of Cell Migration Proton-transporting Two-sector ATPase Complex Neuron Projection Organization Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Postsynapse Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Neuron Projection Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Long-term Synaptic Potentiation Proton Motive Force-driven Mitochondrial ATP Synthesis Estrous Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Transcription-coupled Nucleotide-excision Repair Cognition Regulation Of Mitotic Cell Cycle Proton Motive Force-driven ATP Synthesis Transmembrane Transporter Complex Negative Regulation Of Cell Population Proliferation Proton-transporting ATP Synthase Activity, Rotational Mechanism Regulation Of Cell Cycle G1/S Phase Transition Regulation Of MiRNA Transcription ATP Biosynthetic Process Protein Tyrosine Kinase Activator Activity Negative Regulation Of Cell Cycle Regulation Of MiRNA Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Serine-type Endopeptidase Inhibitor Activity Regulation Of Epithelial Cell Proliferation MHC Class I Protein Binding Ovulation Cycle Dendritic Spine Morphogenesis Nervous System Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Auditory Stimulus Proton-transporting ATP Synthase Complex Transcription Elongation Factor Complex Positive Regulation Of Peptidyl-serine Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process	Transcription Regulator Complex Positive Regulation Of Transcription By RNA Polymerase II Paraxial Mesoderm Morphogenesis Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Binding Regulation Of RNA Biosynthetic Process Mesoderm Morphogenesis Pericardium Development Transcription Coactivator Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific SMAD Protein Complex Trophoblast Cell Migration Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Heteromeric SMAD Protein Complex Chromatin Binding Nucleobase-containing Compound Biosynthetic Process Embryonic Foregut Morphogenesis Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin DNA Binding Nodal Signaling Pathway Co-SMAD Binding Primary MiRNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Differentiation Nucleoplasm Nucleus Liver Development Osteoblast Development I-SMAD Binding Ubiquitin Protein Ligase Binding Transforming Growth Factor Beta Receptor Binding Negative Regulation Of Cell Differentiation Negative Regulation Of Multicellular Organismal Process Double-stranded DNA Binding Protein-containing Complex Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Signal Transduction Response To Virus Response To Angiotensin R-SMAD Binding Negative Regulation Of MiRNA Transcription
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