RHOU and CFAP100

Number of citations of the paper that reports this interaction (PubMedID 26598620)
63

Data Source:
BioGRID (pull down)

		RHOU	CFAP100
Description		ras homolog family member U	cilia and flagella associated protein 100
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GO Annotations	Cellular Component	Golgi Membrane Podosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Endosome Membrane Membrane Cell Projection Anchoring Junction	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Cell Projection Axonemal Doublet Microtubule
	Molecular Function	Nucleotide Binding GTPase Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Metal Ion Binding	Protein Binding Dynein Complex Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Endocytosis Cytoskeleton Organization Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cell Shape Rac Protein Signal Transduction Establishment Of Cell Polarity Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Focal Adhesion Disassembly Positive Regulation Of Protein Targeting To Mitochondrion	Cilium Movement Inner Dynein Arm Assembly
Pathways		Interleukin-4 and Interleukin-13 signaling RHOU GTPase cycle RHOU GTPase cycle
Drugs
Diseases
GWAS		Aging ( 22773346) Basal cell carcinoma ( 18849993 24403052 25855136 27539887 33549134) Chronic lymphocytic leukemia ( 28165464) Dental caries ( 23259602) Endometriosis ( 20844546) Leukoderma in response to rhododendrol ( 32558222) Mercury levels ( 26025379) Non-melanoma skin cancer ( 29739929) Response to antidepressants in depression ( 27622933) Type 2 diabetes ( 23300278)
Interacting Genes		126 interacting genes: ACAD8 ADM2 ALG13 ANGPT4 ANXA4 ANXA6 AP1S1 ARHGEF25 AS3MT ATP5MG ATP6AP1 BDNF BMAL1 BNIPL BRF1 BRINP3 C14orf119 CDKL4 CFAP100 CHRNA4 CLEC7A CPNE3 CTCF CUL5 DACT2 DMRT2 DNM2 DOK4 DSCR8 EIF4B ELP5 EMC2 ERF ERO1A FAM110B FCHO2 FKBP15 GALNTL5 GLI3 GPRIN2 GRB2 H2BC14 HCAR1 HINT3 HSD17B13 ID2 IFFO1 IL17F INSM2 JAM3 KAAG1 KIAA1191 KLRC3 LANCL2 LARS2 LAYN LMO7 LYL1 ME3 MOS MRAS MRPL15 NCK1 NCR1 NPM3 NR1H2 NRBF2 NXPH4 OXCT2 P4HTM PAK1 PAK4 PCDHGA4 PDLIM3 PGK1 PIP5K1A PLCG1 PLEK PLOD3 POT1 PRB1 PRPF18 PSMA4 PXN QTRT1 RAB40A RAD51D RALBP1 RASSF1 RBIS RPL23AP5 RPS15A RPS17P16 S100A4 SEC14L4 SEMA3G SEPTIN6 SIVA1 SKIC2 SLC26A1 SNU13 SOX4 SSC4D STX16 SYK TCN2 TEKT2 TMEM106A TMEM169 TMEM255B TRIM59 USP37 UTP3 VWA5A WNT6 XPA ZFAND2B ZFP64 ZKSCAN7 ZNF117 ZNF177 ZNF20 ZNF569 ZNF625 ZNF747 ZNF84	6 interacting genes: KDM1A RHOU SUV39H1 SUV39H2 SYCE1 TRIM54
Entrez ID		58480	348807
HPRD ID		06965	08805
Ensembl ID		ENSG00000116574	ENSG00000163885
Uniprot IDs		Q7L0Q8	Q494V2
PDB IDs		2Q3H	8J07
Enriched GO Terms of Interacting Partners?		Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin	Histone H3K9 Trimethyltransferase Activity Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Histone H3 Methyltransferase Activity Chromosome Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Epigenetic Regulation Of Gene Expression Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Chromatin Remodeling ENoSc Complex Circadian Rhythm Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Chromosome, Centromeric Region Cellular Response To Oxygen Levels Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Protein Demethylase Activity RDNA Heterochromatin MRF Binding Methylation Chromatin Organization Response To Fungicide Guanine Metabolic Process Histone H3K9me2 Methyltransferase Activity RDNA Heterochromatin Formation Regulation Of DNA Repair Histone H3K4 Demethylase Activity Positive Regulation Of Focal Adhesion Disassembly Central Element Regulation Of Transcription By Glucose Rhythmic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Histone H3K9 Demethylase Activity Chromatin Silencing Complex Response To Hypoxia Cell Differentiation Positive Regulation Of Cell Size Nuclear Lamina Response To Decreased Oxygen Levels Facultative Heterochromatin Formation DNA Repair Complex Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Response To Oxygen Levels Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA-templated Transcription
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