RHOU

Gene Name		ras homolog family member U
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Podosome Cytosol Plasma Membrane Focal Adhesion Cell Projection
	Molecular Function	GTPase Activity Protein Binding GTP Binding Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Cytoskeleton Organization Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Rac Protein Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Aging ( 22773346) Basal cell carcinoma ( 18849993) Dental caries ( 23259602) Endometriosis ( 20844546) Type 2 diabetes ( 23300278)
Protein-protein Interactions		4 interactors: GRB2 NCK1 PAK1 PLCG1
Entrez ID		58480
HPRD ID		06965
Ensembl ID		ENSG00000116574
Uniprot IDs		Q7L0Q8
PDB IDs		2Q3H
Enriched GO Terms of Interacting Partners?		Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Immune Response-regulating Signaling Pathway Axonogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Development T Cell Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Positive Regulation Of Immune Response Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Antigen Receptor-mediated Signaling Pathway Cell Morphogenesis Involved In Differentiation Innate Immune Response Neuron Projection Development Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Cell Motility Positive Regulation Of Cytoskeleton Organization Positive Regulation Of T Cell Activation Neuron Development Positive Regulation Of Homotypic Cell-cell Adhesion Fc-epsilon Receptor Signaling Pathway Cell Morphogenesis Positive Regulation Of Cell-cell Adhesion Neuron Differentiation Cell Projection Organization Regulation Of T Cell Activation Positive Regulation Of Cell Activation Locomotion Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Component Biogenesis Immune Response Regulation Of Immune System Process Regulation Of Phosphorylation Defense Response Regulation Of Actin Cytoskeleton Organization Vesicle-mediated Transport
Tagcloud ?		adaptor avidity calorimetric chicken compensate converge coupling crk crk1 employs extended grb2 isothermal itc nck nck1 noncatalytic nwrch1 p120 pxxp sedimentation sh3 specificities src tight tightly titration wrch1