RHOU and GALNTL5

Number of citations of the paper that reports this interaction (PubMedID 26598620)
63

Data Source:
BioGRID (pull down)

		RHOU	GALNTL5
Description		ras homolog family member U	polypeptide N-acetylgalactosaminyltransferase like 5
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Podosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Endosome Membrane Membrane Cell Projection Anchoring Junction	Endosome Golgi Apparatus Membrane Late Endosome Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Metal Ion Binding	Glycosyltransferase Activity Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Endocytosis Cytoskeleton Organization Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cell Shape Rac Protein Signal Transduction Establishment Of Cell Polarity Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Focal Adhesion Disassembly Positive Regulation Of Protein Targeting To Mitochondrion	Protein Glycosylation Spermatogenesis Spermatid Development Cell Differentiation
Pathways		Interleukin-4 and Interleukin-13 signaling RHOU GTPase cycle RHOU GTPase cycle	O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Aging ( 22773346) Basal cell carcinoma ( 18849993 24403052 25855136 27539887 33549134) Chronic lymphocytic leukemia ( 28165464) Dental caries ( 23259602) Endometriosis ( 20844546) Leukoderma in response to rhododendrol ( 32558222) Mercury levels ( 26025379) Non-melanoma skin cancer ( 29739929) Response to antidepressants in depression ( 27622933) Type 2 diabetes ( 23300278)	Gout ( 31578528) Kidney function decline traits ( 25493955) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		126 interacting genes: ACAD8 ADM2 ALG13 ANGPT4 ANXA4 ANXA6 AP1S1 ARHGEF25 AS3MT ATP5MG ATP6AP1 BDNF BMAL1 BNIPL BRF1 BRINP3 C14orf119 CDKL4 CFAP100 CHRNA4 CLEC7A CPNE3 CTCF CUL5 DACT2 DMRT2 DNM2 DOK4 DSCR8 EIF4B ELP5 EMC2 ERF ERO1A FAM110B FCHO2 FKBP15 GALNTL5 GLI3 GPRIN2 GRB2 H2BC14 HCAR1 HINT3 HSD17B13 ID2 IFFO1 IL17F INSM2 JAM3 KAAG1 KIAA1191 KLRC3 LANCL2 LARS2 LAYN LMO7 LYL1 ME3 MOS MRAS MRPL15 NCK1 NCR1 NPM3 NR1H2 NRBF2 NXPH4 OXCT2 P4HTM PAK1 PAK4 PCDHGA4 PDLIM3 PGK1 PIP5K1A PLCG1 PLEK PLOD3 POT1 PRB1 PRPF18 PSMA4 PXN QTRT1 RAB40A RAD51D RALBP1 RASSF1 RBIS RPL23AP5 RPS15A RPS17P16 S100A4 SEC14L4 SEMA3G SEPTIN6 SIVA1 SKIC2 SLC26A1 SNU13 SOX4 SSC4D STX16 SYK TCN2 TEKT2 TMEM106A TMEM169 TMEM255B TRIM59 USP37 UTP3 VWA5A WNT6 XPA ZFAND2B ZFP64 ZKSCAN7 ZNF117 ZNF177 ZNF20 ZNF569 ZNF625 ZNF747 ZNF84	2 interacting genes: RHOU TP53BP1
Entrez ID		58480	168391
HPRD ID		06965	13565
Ensembl ID		ENSG00000116574	ENSG00000106648
Uniprot IDs		Q7L0Q8	Q7Z4T8
PDB IDs		2Q3H
Enriched GO Terms of Interacting Partners?		Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin	Cellular Response To X-ray Double-strand Break Repair Via Classical Nonhomologous End Joining Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Histone H4K20me Methyltransferase Activity Ubiquitin-modified Histone Reader Activity Histone H4K20me2 Reader Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of DNA-templated DNA Replication Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Focal Adhesion Disassembly DNA Strand Resection Involved In Replication Fork Processing DNA Repair Complex Replication Fork Negative Regulation Of DNA Replication Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response Telomeric DNA Binding Histone Reader Activity Positive Regulation Of Isotype Switching Response To X-ray Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Localization To Site Of Double-strand Break Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Double-strand Break Repair Rac Protein Signal Transduction Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Podosome Positive Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of DNA Repair Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of DNA Recombination Positive Regulation Of Immunoglobulin Production Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Damaged DNA Binding Positive Regulation Of DNA Recombination P53 Binding Cellular Response To Ionizing Radiation Regulation Of Immunoglobulin Production Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of B Cell Activation Regulation Of Cell-substrate Junction Organization Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Intracellular Signal Transduction Establishment Of Cell Polarity
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