CFAP100 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		CFAP100	SUV39H2
Description		cilia and flagella associated protein 100	SUV39H2 histone lysine methyltransferase
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Cell Projection Axonemal Doublet Microtubule	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding Dynein Complex Binding	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Cilium Movement Inner Dynein Arm Assembly	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		6 interacting genes: KDM1A RHOU SUV39H1 SUV39H2 SYCE1 TRIM54	43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57
Entrez ID		348807	79723
HPRD ID		08805	07580
Ensembl ID		ENSG00000163885	ENSG00000152455
Uniprot IDs		Q494V2	Q9H5I1
PDB IDs		8J07	2R3A 6P0R
Enriched GO Terms of Interacting Partners?		Histone H3K9 Trimethyltransferase Activity Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Histone H3 Methyltransferase Activity Chromosome Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Epigenetic Regulation Of Gene Expression Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Chromatin Remodeling ENoSc Complex Circadian Rhythm Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Chromosome, Centromeric Region Cellular Response To Oxygen Levels Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Protein Demethylase Activity RDNA Heterochromatin MRF Binding Methylation Chromatin Organization Response To Fungicide Guanine Metabolic Process Histone H3K9me2 Methyltransferase Activity RDNA Heterochromatin Formation Regulation Of DNA Repair Histone H3K4 Demethylase Activity Positive Regulation Of Focal Adhesion Disassembly Central Element Regulation Of Transcription By Glucose Rhythmic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Histone H3K9 Demethylase Activity Chromatin Silencing Complex Response To Hypoxia Cell Differentiation Positive Regulation Of Cell Size Nuclear Lamina Response To Decreased Oxygen Levels Facultative Heterochromatin Formation DNA Repair Complex Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Response To Oxygen Levels Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA-templated Transcription	Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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