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SPTBN4 and GADD45A
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
SPTBN4
GADD45A
Gene Name
spectrin, beta, non-erythrocytic 4
growth arrest and DNA-damage-inducible, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Spectrin
Membrane
Nuclear Matrix
PML Body
Node Of Ranvier
Paranode Region Of Axon
Neuronal Cell Body
Axon Initial Segment
Axon Hillock
Extracellular Vesicular Exosome
Cell Body Fiber
Nucleus
Cytoplasm
Molecular Function
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Phospholipid Binding
Phosphatase Binding
Ankyrin Binding
Spectrin Binding
Core Promoter Binding
Protein Binding
Biological Process
Regulation Of Sodium Ion Transport
Cytoskeletal Anchoring At Plasma Membrane
Axonogenesis
Axon Guidance
Sensory Perception Of Sound
Adult Walking Behavior
Fertilization
Negative Regulation Of Heart Rate
Vesicle-mediated Transport
Transmission Of Nerve Impulse
Central Nervous System Projection Neuron Axonogenesis
Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Multicellular Organism Growth
Clustering Of Voltage-gated Sodium Channels
Actin Filament Capping
Cardiac Conduction
Establishment Of Protein Localization To Plasma Membrane
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Activation Of MAPKKK Activity
DNA Repair
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Cell Cycle Arrest
Centrosome Cycle
Signal Transduction In Response To DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of JNK Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Ionizing Radiation
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Interaction between L1 and Ankyrins
Axon guidance
L1CAM interactions
NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
ANK3
CDC37
CELSR3
CENPU
DISC1
GADD45A
GSK3B
NEK2
PFDN1
PTPRN
PTPRN2
RPS6KA6
65 interactors:
ADAP1
ASCC2
AURKA
BAG6
C14orf1
CCNB1
CDK1
CDK11A
CDKN1A
CENPB
CHD3
CLEC3B
DCTN2
DNAJC13
EEF1A1
EEF1G
FAM83D
FAS
FBN3
FTL
GADD45GIP1
GAPDH
GBP2
GNB2
HIST1H1A
HIST1H2AL
HIST2H2BE
HIST3H3
HIST4H4
IGHM
IGSF21
JMJD1C
KHSRP
LMO4
MAP3K4
MAPK14
MASP1
MDM2
MICAL1
MIDN
MPP1
NPM1
NRBP1
NUCB2
PCNA
PFKFB4
PPARA
PSMC3
PTN
PTPRK
QARS
RAI1
RBPJ
RPS2
RXRA
SH3GLB1
SPTBN4
SYNE4
TLE1
TP53
UBE2D1
UBR1
VIM
ZHX1
ZNF135
Entrez ID
57731
1647
HPRD ID
09372
00528
Ensembl ID
ENSG00000160460
ENSG00000116717
Uniprot IDs
C9JY79
Q9H254
A5JUZ3
P24522
PDB IDs
2KG4
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Organelle Organization
Axon Development
Cytoskeleton Organization
Locomotion
Regulation Of Cellular Process
Telencephalon Development
Centrosome Cycle
Nervous System Development
Regulation Of Protein Localization
Movement Of Cell Or Subcellular Component
Maintenance Of Protein Location In Plasma Membrane
Negative Regulation Of Centriole-centriole Cohesion
Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Neuron Projection Development
Multicellular Organismal Development
Cell Projection Morphogenesis
Cellular Response To Mechanical Stimulus
Generation Of Neurons
Cell Part Morphogenesis
Anatomical Structure Development
Axon Guidance
Neurogenesis
Negative Regulation Of Phosphorylation
Neuron Development
Signal Transduction In Response To DNA Damage
Negative Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Cell Communication By Electrical Coupling
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Superior Temporal Gyrus Development
Dense Core Granule Maturation
Canonical Wnt Signaling Pathway
Central Nervous System Development
Signal Transduction
Centrosome Organization
Negative Regulation Of Binding
Microtubule Cytoskeleton Organization
Forebrain Development
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cell Cycle Process
Cell Morphogenesis
Microtubule Organizing Center Organization
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Regulation Of Centriole-centriole Cohesion
Developmental Process
Protein Localization
Neuron Differentiation
Signaling
Cell Projection Organization
Regulation Of Metabolic Process
Cell Cycle
Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cellular Response To Organic Substance
Regulation Of Protein Metabolic Process
Organelle Organization
DNA Packaging
DNA Conformation Change
Negative Regulation Of Cellular Metabolic Process
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromosome Organization
Cell Aging
Protein Complex Assembly
Chromatin Organization
Negative Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Cell Death
Death
Positive Regulation Of Protein Metabolic Process
Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Catabolic Process
Response To Organic Substance
DNA Damage Checkpoint
Chromatin Assembly Or Disassembly
Stress-induced Premature Senescence
Immune Response
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of Gene Expression
Mitotic DNA Damage Checkpoint
Immune System Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Innate Immune Response
Mitotic DNA Integrity Checkpoint
Response To Toxic Substance
Positive Regulation Of Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Cellular Response To Oxygen Levels
Tagcloud
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Intersection)
?