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SPTBN4 and CDC37
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
SPTBN4
CDC37
Gene Name
spectrin, beta, non-erythrocytic 4
cell division cycle 37
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Spectrin
Membrane
Nuclear Matrix
PML Body
Node Of Ranvier
Paranode Region Of Axon
Neuronal Cell Body
Axon Initial Segment
Axon Hillock
Extracellular Vesicular Exosome
Cell Body Fiber
Cytoplasm
Cytosol
Ruffle Membrane
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Phospholipid Binding
Phosphatase Binding
Ankyrin Binding
Spectrin Binding
Protein Binding
Kinase Binding
Heat Shock Protein Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Kinase B Binding
Unfolded Protein Binding
Chaperone Binding
Hsp90 Protein Binding
Biological Process
Regulation Of Sodium Ion Transport
Cytoskeletal Anchoring At Plasma Membrane
Axonogenesis
Axon Guidance
Sensory Perception Of Sound
Adult Walking Behavior
Fertilization
Negative Regulation Of Heart Rate
Vesicle-mediated Transport
Transmission Of Nerve Impulse
Central Nervous System Projection Neuron Axonogenesis
Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Multicellular Organism Growth
Clustering Of Voltage-gated Sodium Channels
Actin Filament Capping
Cardiac Conduction
Establishment Of Protein Localization To Plasma Membrane
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Folding
Protein Targeting
Protein Stabilization
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Type I Interferon-mediated Signaling Pathway
Pathways
Interaction between L1 and Ankyrins
Axon guidance
L1CAM interactions
NCAM signaling for neurite out-growth
Signaling by ERBB2
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Signaling by EGFR in Cancer
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by EGFRvIII in Cancer
Constitutive Signaling by EGFRvIII
Drugs
Diseases
GWAS
Multiple sclerosis (
21833088
)
Protein-Protein Interactions
12 interactors:
ANK3
CDC37
CELSR3
CENPU
DISC1
GADD45A
GSK3B
NEK2
PFDN1
PTPRN
PTPRN2
RPS6KA6
72 interactors:
A2M
APOE
APP
AR
BTBD10
C19orf44
CC2D1A
CDC37L1
CDK2
CDK3
CDK4
CDK5
CDK6
CDK7
CHGA
CHUK
CKS1B
CKS2
CRYM
CSNK2A1
CSNK2A2
CYP2C9
DCTN1
DEAF1
ECSIT
EIF2AK1
ELAVL3
EXOSC1
FBXL12
FBXW4
GCDH
GCH1
HSP90AA1
IFIT3
IFIT5
IKBKB
IKBKE
IKBKG
IMMT
LONP1
LOXL4
LUC7L2
MAP3K14
MAP3K3
MGEA5
MTOR
MZT2B
NCOA5
NOS3
NR2C2
PPHLN1
PRAM1
PRDX2
PRMT1
PSME1
RAD23A
RNF32
RPS15A
SAFB
SNX5
SPTBN4
SQSTM1
SRC
STAMBPL1
STIP1
STK11
TBK1
UBE2I
ZNF205
ZNF235
ZNF266
ZNF667
Entrez ID
57731
11140
HPRD ID
09372
05456
Ensembl ID
ENSG00000160460
ENSG00000105401
Uniprot IDs
C9JY79
Q9H254
Q16543
PDB IDs
1US7
2K5B
2W0G
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Organelle Organization
Axon Development
Cytoskeleton Organization
Locomotion
Regulation Of Cellular Process
Telencephalon Development
Centrosome Cycle
Nervous System Development
Regulation Of Protein Localization
Movement Of Cell Or Subcellular Component
Maintenance Of Protein Location In Plasma Membrane
Negative Regulation Of Centriole-centriole Cohesion
Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Neuron Projection Development
Multicellular Organismal Development
Cell Projection Morphogenesis
Cellular Response To Mechanical Stimulus
Generation Of Neurons
Cell Part Morphogenesis
Anatomical Structure Development
Axon Guidance
Neurogenesis
Negative Regulation Of Phosphorylation
Neuron Development
Signal Transduction In Response To DNA Damage
Negative Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Cell Communication By Electrical Coupling
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Superior Temporal Gyrus Development
Dense Core Granule Maturation
Canonical Wnt Signaling Pathway
Central Nervous System Development
Signal Transduction
Centrosome Organization
Negative Regulation Of Binding
Microtubule Cytoskeleton Organization
Forebrain Development
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cell Cycle Process
Cell Morphogenesis
Microtubule Organizing Center Organization
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Regulation Of Centriole-centriole Cohesion
Developmental Process
Protein Localization
Neuron Differentiation
Signaling
Cell Projection Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Metabolic Process
Regulation Of Protein Metabolic Process
Protein Phosphorylation
Regulation Of Phosphorylation
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Protein Phosphorylation
Response To Stress
Cellular Metabolic Process
Response To External Stimulus
Phosphorylation
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Kinase Activity
I-kappaB Kinase/NF-kappaB Signaling
Response To Stimulus
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Protein Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Mitotic Cell Cycle Phase Transition
Response To Virus
Cell Cycle Phase Transition
Catabolic Process
Regulation Of Catalytic Activity
Intracellular Receptor Signaling Pathway
Cell Cycle
Regulation Of Gene Expression
Positive Regulation Of Protein Metabolic Process
Protein Metabolic Process
Innate Immune Response
Positive Regulation Of Cellular Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Process
Phosphate-containing Compound Metabolic Process
Cellular Protein Modification Process
Cell Cycle Process
Regulation Of Signal Transduction
Protein Catabolic Process
Mitotic Cell Cycle
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Signaling
Toll-like Receptor 3 Signaling Pathway
Regulation Of Signaling
Positive Regulation Of Signal Transduction
Cellular Response To Stimulus
Tagcloud
?
base
chick
clusters
conforms
consensus
copies
emphasize
exons
finger
flanking
gctat
ggg
glycosaminoglycans
homeodomain
hsp90
introns
kilobases
mzf1
pair
presumptive
promotion
reorganization
repetitive
s8
sizes
sp1
stabilization
striking
tatgggga
Tagcloud (Difference)
?
base
chick
clusters
conforms
consensus
copies
emphasize
exons
finger
flanking
gctat
ggg
glycosaminoglycans
homeodomain
hsp90
introns
kilobases
mzf1
pair
presumptive
promotion
reorganization
repetitive
s8
sizes
sp1
stabilization
striking
tatgggga
Tagcloud (Intersection)
?