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SPTBN4 and ANK3
Number of citations of the paper that reports this interaction (PMID
11807096
)
53
Data Source:
HPRD
(in vivo)
SPTBN4
ANK3
Gene Name
spectrin, beta, non-erythrocytic 4
ankyrin 3, node of Ranvier (ankyrin G)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Spectrin
Membrane
Nuclear Matrix
PML Body
Node Of Ranvier
Paranode Region Of Axon
Neuronal Cell Body
Axon Initial Segment
Axon Hillock
Extracellular Vesicular Exosome
Cell Body Fiber
Lysosome
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Tight Junction
Basal Plasma Membrane
Cell Surface
Intercalated Disc
Spectrin-associated Cytoskeleton
Basolateral Plasma Membrane
Lateral Plasma Membrane
Sarcoplasmic Reticulum
Z Disc
T-tubule
Dendrite
Neuromuscular Junction
Node Of Ranvier
Paranode Region Of Axon
Sarcolemma
Costamere
Axon Initial Segment
Postsynaptic Membrane
Molecular Function
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Phospholipid Binding
Phosphatase Binding
Ankyrin Binding
Spectrin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Cytoskeletal Protein Binding
Spectrin Binding
Protein Binding, Bridging
Ion Channel Binding
Cadherin Binding
Biological Process
Regulation Of Sodium Ion Transport
Cytoskeletal Anchoring At Plasma Membrane
Axonogenesis
Axon Guidance
Sensory Perception Of Sound
Adult Walking Behavior
Fertilization
Negative Regulation Of Heart Rate
Vesicle-mediated Transport
Transmission Of Nerve Impulse
Central Nervous System Projection Neuron Axonogenesis
Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Multicellular Organism Growth
Clustering Of Voltage-gated Sodium Channels
Actin Filament Capping
Cardiac Conduction
Establishment Of Protein Localization To Plasma Membrane
Mitotic Cytokinesis
Plasma Membrane Organization
Cytoskeletal Anchoring At Plasma Membrane
Signal Transduction
Axonogenesis
Axon Guidance
Neuromuscular Junction Development
Positive Regulation Of Gene Expression
Positive Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Sodium Ion Transport
Magnesium Ion Homeostasis
Neuronal Action Potential
Positive Regulation Of Homotypic Cell-cell Adhesion
Golgi To Plasma Membrane Protein Transport
Regulation Of Potassium Ion Transport
Establishment Of Protein Localization
Positive Regulation Of Membrane Potential
Cellular Response To Magnesium Ion
Membrane Assembly
Protein Localization To Plasma Membrane
Maintenance Of Protein Location In Plasma Membrane
Protein Targeting To Plasma Membrane
Positive Regulation Of Protein Targeting To Membrane
Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Interaction between L1 and Ankyrins
Axon guidance
L1CAM interactions
NCAM signaling for neurite out-growth
Interaction between L1 and Ankyrins
Axon guidance
L1CAM interactions
Drugs
Diseases
GWAS
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Bipolar disorder (
22182935
21926972
18711365
)
Bipolar disorder and major depressive disorder (combined) (
20351715
)
Schizophrenia (
20185149
)
Protein-Protein Interactions
12 interactors:
ANK3
CDC37
CELSR3
CENPU
DISC1
GADD45A
GSK3B
NEK2
PFDN1
PTPRN
PTPRN2
RPS6KA6
12 interactors:
FADD
FAS
HOOK1
KCNC1
MAPK6
PIK3R1
SCN1B
SCN2A
SCNN1B
SMAD2
SMAD3
SPTBN4
Entrez ID
57731
288
HPRD ID
09372
02715
Ensembl ID
ENSG00000160460
ENSG00000151150
Uniprot IDs
C9JY79
Q9H254
Q12955
Q8NAK2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Organelle Organization
Axon Development
Cytoskeleton Organization
Locomotion
Regulation Of Cellular Process
Telencephalon Development
Centrosome Cycle
Nervous System Development
Regulation Of Protein Localization
Movement Of Cell Or Subcellular Component
Maintenance Of Protein Location In Plasma Membrane
Negative Regulation Of Centriole-centriole Cohesion
Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Neuron Projection Development
Multicellular Organismal Development
Cell Projection Morphogenesis
Cellular Response To Mechanical Stimulus
Generation Of Neurons
Cell Part Morphogenesis
Anatomical Structure Development
Axon Guidance
Neurogenesis
Negative Regulation Of Phosphorylation
Neuron Development
Signal Transduction In Response To DNA Damage
Negative Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Cell Communication By Electrical Coupling
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Superior Temporal Gyrus Development
Dense Core Granule Maturation
Canonical Wnt Signaling Pathway
Central Nervous System Development
Signal Transduction
Centrosome Organization
Negative Regulation Of Binding
Microtubule Cytoskeleton Organization
Forebrain Development
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cell Cycle Process
Cell Morphogenesis
Microtubule Organizing Center Organization
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Regulation Of Centriole-centriole Cohesion
Developmental Process
Protein Localization
Neuron Differentiation
Signaling
Cell Projection Organization
Extrinsic Apoptotic Signaling Pathway
Motor Neuron Apoptotic Process
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Neuron Apoptotic Process
Transmission Of Nerve Impulse
Necroptotic Signaling Pathway
Primary MiRNA Processing
Neuron Death
SMAD Protein Complex Assembly
Paraxial Mesoderm Morphogenesis
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Communication
Nodal Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity
Embryonic Foregut Morphogenesis
Positive Regulation Of Endopeptidase Activity
Lymphocyte Activation
Foregut Morphogenesis
Paraxial Mesoderm Development
Positive Regulation Of Peptidase Activity
Cell Differentiation
Regulation Of Cell Differentiation
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Multicellular Organismal Development
Pericardium Development
Apoptotic Process
Leukocyte Activation
Anatomical Structure Development
Programmed Cell Death
Regulation Of Myeloid Cell Differentiation
Signal Transduction Involved In Regulation Of Gene Expression
Transport
Protein Complex Assembly
Cell Death
Death
Activin Receptor Signaling Pathway
Positive Regulation Of Epithelial To Mesenchymal Transition
Necroptotic Process
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Abiotic Stimulus
Sodium Ion Transmembrane Transport
Regulation Of Cysteine-type Endopeptidase Activity
Gene Silencing By MiRNA
Membrane Depolarization During Action Potential
Tagcloud
?
add
adipocytes
algorithms
backward
bd
bipolar
categorical
chi2
contingency
doi
escitalopram
expand
lithium
meaningful
mp
ordinal
pkc
psychiatry
publication
remove
rs10761482
snp
stepwise
suffer
swedish
switches
tables
takes
variance
Tagcloud (Difference)
?
add
adipocytes
algorithms
backward
bd
bipolar
categorical
chi2
contingency
doi
escitalopram
expand
lithium
meaningful
mp
ordinal
pkc
psychiatry
publication
remove
rs10761482
snp
stepwise
suffer
swedish
switches
tables
takes
variance
Tagcloud (Intersection)
?