SPTBN4 and CELSR3

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		SPTBN4	CELSR3
Gene Name		spectrin, beta, non-erythrocytic 4	cadherin, EGF LAG seven-pass G-type receptor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Adherens Junction Spectrin Membrane Nuclear Matrix PML Body Node Of Ranvier Paranode Region Of Axon Neuronal Cell Body Axon Initial Segment Axon Hillock Extracellular Vesicular Exosome Cell Body Fiber	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Phospholipid Binding Phosphatase Binding Ankyrin Binding Spectrin Binding	G-protein Coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Sodium Ion Transport Cytoskeletal Anchoring At Plasma Membrane Axonogenesis Axon Guidance Sensory Perception Of Sound Adult Walking Behavior Fertilization Negative Regulation Of Heart Rate Vesicle-mediated Transport Transmission Of Nerve Impulse Central Nervous System Projection Neuron Axonogenesis Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Multicellular Organism Growth Clustering Of Voltage-gated Sodium Channels Actin Filament Capping Cardiac Conduction Establishment Of Protein Localization To Plasma Membrane	Neuron Migration Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Cilium Assembly
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ANK3 CDC37 CELSR3 CENPU DISC1 GADD45A GSK3B NEK2 PFDN1 PTPRN PTPRN2 RPS6KA6	11 interactors: CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA
Entrez ID		57731	1951
HPRD ID		09372	09179
Ensembl ID		ENSG00000160460	ENSG00000008300
Uniprot IDs		C9JY79 Q9H254	Q9NYQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Organelle Organization Axon Development Cytoskeleton Organization Locomotion Regulation Of Cellular Process Telencephalon Development Centrosome Cycle Nervous System Development Regulation Of Protein Localization Movement Of Cell Or Subcellular Component Maintenance Of Protein Location In Plasma Membrane Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Neuron Projection Development Multicellular Organismal Development Cell Projection Morphogenesis Cellular Response To Mechanical Stimulus Generation Of Neurons Cell Part Morphogenesis Anatomical Structure Development Axon Guidance Neurogenesis Negative Regulation Of Phosphorylation Neuron Development Signal Transduction In Response To DNA Damage Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Delayed Rectifier Potassium Channel Activity Superior Temporal Gyrus Development Dense Core Granule Maturation Canonical Wnt Signaling Pathway Central Nervous System Development Signal Transduction Centrosome Organization Negative Regulation Of Binding Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Cycle Process Cell Morphogenesis Microtubule Organizing Center Organization Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Regulation Of Centriole-centriole Cohesion Developmental Process Protein Localization Neuron Differentiation Signaling Cell Projection Organization	Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Organelle Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Histone H2A K63-linked Ubiquitination Late Endosome To Golgi Transport Negative Regulation Of Protein Complex Assembly Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Intracellular Distribution Of Mitochondria Negative Regulation Of Cytoskeleton Organization Adult Behavior Movement Of Cell Or Subcellular Component Regulation Of Protein K63-linked Ubiquitination Regulation Of Actin Filament Polymerization Intraciliary Retrograde Transport Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Clustering Of Voltage-gated Sodium Channels Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Heart Rate Cell Projection Morphogenesis Cytoskeletal Anchoring At Plasma Membrane Cell Part Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Hemidesmosome Assembly Organelle Organization Cellular Component Assembly Protein Localization To Cilium Regulation Of Cellular Component Organization Mitochondrion Distribution
Tagcloud ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Difference) ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Intersection) ?