Wiki-Pi
About
Search
People
Updates
Search
PRKAA2 and ACACA
Number of citations of the paper that reports this interaction (PubMedID
11052978
)
0
Data Source:
HPRD
(in vitro)
PRKAA2
ACACA
Description
protein kinase AMP-activated catalytic subunit alpha 2
acetyl-CoA carboxylase alpha
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Nucleotide-activated Protein Kinase Complex
Ciliary Basal Body
Neuronal Cell Body
Fibrillar Center
Cytoplasm
Mitochondrion
Cytosol
Actin Cytoskeleton
Molecular Function
Nucleotide Binding
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
Protein Serine Kinase Activity
Histone H2BS36 Kinase Activity
Nucleotide Binding
Catalytic Activity
Acetyl-CoA Carboxylase Activity
Protein Binding
ATP Binding
Ligase Activity
Identical Protein Binding
Metal Ion Binding
Biological Process
Cytoplasmic Translation
Chromatin Organization
Chromatin Remodeling
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Phosphatidylethanolamine Biosynthetic Process
Phosphatidylcholine Biosynthetic Process
Steroid Biosynthetic Process
Cholesterol Biosynthetic Process
Autophagy
Signal Transduction
Steroid Metabolic Process
Cholesterol Metabolic Process
Lipid Biosynthetic Process
Cellular Response To Starvation
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Response To Muscle Activity
Wnt Signaling Pathway
Sterol Biosynthetic Process
Positive Regulation Of Macroautophagy
Regulation Of Macroautophagy
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Cellular Response To Amino Acid Starvation
Cellular Response To Oxidative Stress
TORC1 Signaling
Cellular Response To Glucose Starvation
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Glycolytic Process
Negative Regulation Of Translational Initiation
Positive Regulation Of Translational Initiation
Rhythmic Process
Fatty Acid Homeostasis
Protein Localization To Lysosome
Regulation Of Stress Granule Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Xenobiotic Stimulus
Protein K6-linked Ubiquitination
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Energy Homeostasis
Hepatocyte Apoptotic Process
Positive Regulation Of Protein Localization
Negative Regulation Of Hepatocyte Apoptotic Process
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Negative Regulation Of Tubulin Deacetylation
Lipid Droplet Disassembly
Protein Localization To Lipid Droplet
Tissue Homeostasis
Acetyl-CoA Metabolic Process
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Acyl-CoA Metabolic Process
Lipid Biosynthetic Process
Fatty-acyl-CoA Biosynthetic Process
Protein Homotetramerization
Lipid Homeostasis
Cellular Response To Prostaglandin E Stimulus
Malonyl-CoA Biosynthetic Process
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine shuttle
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Nuclear events mediated by NFE2L2
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
ChREBP activates metabolic gene expression
Biotin transport and metabolism
Carnitine shuttle
Activation of gene expression by SREBF (SREBP)
Defective HLCS causes multiple carboxylase deficiency
Fatty acyl-CoA biosynthesis
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Biotin
Diseases
GWAS
Lymphocyte count (
22286170
)
Daytime nap (
33568662
)
Ovarian cancer (
23535730
)
Interacting Genes
122 interacting genes:
ABI1
ABI2
ACACA
ACACB
AIMP2
AKAP8L
AMOT
AMOTL2
ANAPC11
APPBP2
ARRDC3
AVPI1
C19orf47
CALCOCO1
CALCOCO2
CCDC172
CCDC33
CCNB1IP1
CDC42EP1
CDR2
CDX4
CPSF7
CTAG2
CYSRT1
DNAAF6
DNM2
DNMT1
DVL3
EEF2K
EMILIN1
EPM2A
EPN2
FNDC3B
FOS
GIGYF1
GLI1
GOLGA2
GOLGA6A
GRAP2
HAT1
HMBOX1
HNF4A
HOMEZ
IKZF1
IKZF3
KCTD1
KCTD9
KIAA1328
KIF16B
KIF24
KIFC3
KRT16
KRT31
KRTAP1-3
KRTAP10-3
KRTAP10-9
L3MBTL3
LCN2
LEP
LZTS2
MKRN3
MORN3
MRFAP1
MTUS2
MYCL
MYOZ1
NAB2
NECAB2
NONO
NOTCH2NLA
NRAP
NRBF2
NUTM1
PBXIP1
PFKFB2
PLEKHN1
PRDM6
PRKAB1
PRKAG1
PRKAR1B
PRKN
PRPH
RASAL3
RBBP7
RBPMS
REL
RFX6
RPTOR
SAXO4
SERTAD3
SKIC2
SLA2
SNW1
SOHLH1
SPRY1
STAC2
STK11
TCF4
TFAP2A
TIFA
TLE5
TMOD1
TRIP13
TRIP6
TSC22D4
UBC
UBE2I
USH1C
USH1G
USHBP1
VPS28
VPS37B
VPS52
WASHC1
WWP1
WWP2
YPEL3
ZBTB8A
ZMYND12
ZNF212
ZNF397
ZSCAN23
15 interacting genes:
APOC1
ATXN1
BRCA1
CHGB
CSNK2A1
CSNK2A2
FGF14
NEIL3
PRKAA1
PRKAA2
PRKAB1
PRKAG1
TRIB1
TRIB2
TRIB3
Entrez ID
5563
31
HPRD ID
02735
01938
Ensembl ID
ENSG00000162409
ENSG00000278540
Uniprot IDs
P54646
Q13085
Q7Z5W8
PDB IDs
2H6D
2LTU
2YZA
3AQV
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6B2E
6BX6
7MYJ
8BIK
2YL2
3COJ
4ASI
6G2D
6G2H
6G2I
8XKZ
8XL0
8XL1
8XL2
Enriched GO Terms of Interacting Partners
?
Protein Binding
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Identical Protein Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Cytosol
Supramolecular Fiber Organization
Cytoplasm
Negative Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Malonyl-CoA Biosynthetic Process
Acetyl-CoA Carboxylase Activity
Nucleus
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Response To Prolactin
Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Cytoskeleton
Cellular Component Assembly
Autophagy
Regulation Of Growth
Transcription Factor Binding
Equilibrioception
Keratin Filament
Microtubule Motor Activity
Cullin Family Protein Binding
Microtubule
Nucleotide-activated Protein Kinase Complex
Ubiquitin-protein Transferase Regulator Activity
AMP-activated Protein Kinase Activity
Fatty Acid Biosynthetic Process
Mitogen-activated Protein Kinase Kinase Binding
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Small Molecule Metabolic Process
Negative Regulation Of Lipid Biosynthetic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Fatty Acid Biosynthetic Process
Histone H2BS36 Kinase Activity
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
Regulation Of Proteasomal Protein Catabolic Process
Protein K6-linked Ubiquitination
Negative Regulation Of Lipid Metabolic Process
Carboxylic Acid Biosynthetic Process
Protein Kinase CK2 Complex
Protein Kinase Activity
Protein Localization To Lipid Droplet
Fatty Acid Metabolic Process
Negative Regulation Of Fatty Acid Metabolic Process
Positive Regulation Of Catabolic Process
Protein Kinase Inhibitor Activity
Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Translational Initiation
Negative Regulation Of Tubulin Deacetylation
CAMP-dependent Protein Kinase Activity
Negative Regulation Of Hepatocyte Apoptotic Process
Cellular Response To Glucose Starvation
Negative Regulation Of Signal Transduction
Regulation Of Protein Catabolic Process
Regulation Of Autophagy
Regulation Of Tubulin Deacetylation
Regulation Of Glycolytic Process
Lipid Droplet Disassembly
Regulation Of Proteolysis
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Lipid Biosynthetic Process
Regulation Of Carbohydrate Catabolic Process
Regulation Of MAP Kinase Activity
Cellular Response To Stress
Negative Regulation Of Metabolic Process
Positive Regulation Of Protein Catabolic Process
Phosphatidylethanolamine Biosynthetic Process
Small Molecule Biosynthetic Process
Negative Regulation Of Intracellular Signal Transduction
Regulation Of ATP Metabolic Process
Regulation Of Protein Deacetylation
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?