APLP2 and APBB3

Number of citations of the paper that reports this interaction (PMID 10081969)
5

Data Source:
HPRD (in vitro)

		APLP2	APBB3
Gene Name		amyloid beta (A4) precursor-like protein 2	amyloid beta (A4) precursor protein-binding, family B, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Actin Cytoskeleton
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	Beta-amyloid Binding Protein Binding Transcription Factor Binding
	Biological Process	Suckling Behavior Cellular Copper Ion Homeostasis Regulation Of Epidermal Growth Factor-activated Receptor Activity G-protein Coupled Receptor Signaling Pathway Mating Behavior Locomotory Behavior Cholesterol Metabolic Process Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Forebrain Development Midbrain Development Regulation Of Protein Binding Neuromuscular Process Controlling Balance	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADIPOR1 AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 VKORC1 ZNF512B	6 interactors: APLP1 APLP2 APP EGFR ERBB2 RAB4A
Entrez ID		334	10307
HPRD ID		00103	04089
Ensembl ID		ENSG00000084234	ENSG00000113108
Uniprot IDs		B4E3I5 Q06481	O95704 Q59EH2 Q96DX9
PDB IDs			2DYQ 2YSC
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Response To Radiation Negative Regulation Of Cell Death Cellular Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Response To Growth Factor Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance Apoptotic Process Response To Cytokine Signal Transduction Programmed Cell Death Response To External Stimulus Cell Death Response To Stimulus Death Positive Regulation Of Metabolic Process Response To Stress Intracellular Signal Transduction Response To Abiotic Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Signaling Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Cell Communication Regulation Of Transcription, DNA-templated Apoptotic Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Leading Edge Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Regulation Of Growth Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of RNA Metabolic Process Regulation Of Cell Adhesion Regulation Of Immune System Process Neurotrophin TRK Receptor Signaling Pathway Response To Hormone	Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Central Nervous System Development Regulation Of ERBB Signaling Pathway Forebrain Development Regulation Of Phosphorus Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Brain Development Regulation Of Kinase Activity Head Development MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cellular Protein Metabolic Process Mating Behavior Regulation Of Translation RNA Polyadenylation Regulation Of Protein Metabolic Process Nervous System Development Regulation Of Protein Phosphorylation Neuromuscular Junction Development Mating Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Signal Transduction Regulation Of Phosphorylation Posttranscriptional Regulation Of Gene Expression Metal Ion Homeostasis Neuromuscular Process Controlling Balance MRNA 3'-end Processing Regulation Of Cellular Ketone Metabolic Process Organ Development Signaling Axonogenesis Cell Communication Cell Surface Receptor Signaling Pathway Feeding Behavior Ion Homeostasis Alkanesulfonate Metabolic Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation RNA 3'-end Processing Behavior Chemotaxis Cholesterol Metabolic Process
Tagcloud ?		allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological
Tagcloud (Difference) ?		allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological
Tagcloud (Intersection) ?