APLP2 and RPL26

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		APLP2	RPL26
Gene Name		amyloid beta (A4) precursor-like protein 2	ribosomal protein L26
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Cytosol Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding
	Biological Process	Suckling Behavior Cellular Copper Ion Homeostasis Regulation Of Epidermal Growth Factor-activated Receptor Activity G-protein Coupled Receptor Signaling Pathway Mating Behavior Locomotory Behavior Cholesterol Metabolic Process Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Forebrain Development Midbrain Development Regulation Of Protein Binding Neuromuscular Process Controlling Balance	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADIPOR1 AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 VKORC1 ZNF512B	6 interactors: APLP2 HNRNPR MDM2 NAA10 NAA15 NAA16
Entrez ID		334	6154
HPRD ID		00103	04746
Ensembl ID		ENSG00000084234	ENSG00000161970
Uniprot IDs		B4E3I5 Q06481	P61254
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Response To Radiation Negative Regulation Of Cell Death Cellular Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Response To Growth Factor Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance Apoptotic Process Response To Cytokine Signal Transduction Programmed Cell Death Response To External Stimulus Cell Death Response To Stimulus Death Positive Regulation Of Metabolic Process Response To Stress Intracellular Signal Transduction Response To Abiotic Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Signaling Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Cell Communication Regulation Of Transcription, DNA-templated Apoptotic Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Leading Edge Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Regulation Of Growth Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of RNA Metabolic Process Regulation Of Cell Adhesion Regulation Of Immune System Process Neurotrophin TRK Receptor Signaling Pathway Response To Hormone	N-terminal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Modification Protein Acetylation Regulation Of Protein Stability Posttranscriptional Regulation Of Gene Expression Protein Stabilization Cellular Response To UV-C Cellular Response To Vitamin B1 N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Response To Vitamin B1 Response To Ether Negative Regulation Of Cell Death Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Response To UV-C Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Proteolysis Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Cellular Protein Modification Process Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Cellular Copper Ion Homeostasis Response To Magnesium Ion Positive Regulation Of Gene Expression Regulation Of Cell Death Cellular Response To Antibiotic Negative Regulation Of Cell Cycle Arrest Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Toxic Substance Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle G1/S Phase Transition Protein Destabilization Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Tagcloud ?		allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological	18s 28s acridine b23 c23 devised exposing fibrillarin gv homogenous hp1alpha impoverished isothiocyanate nlb nlbs nobox nsn nucleolar nucleoli nucleolin nucleolus nucleophosmin oocytes rrnas sc35 storing surrounded ubf unequivocally
Tagcloud (Difference) ?		allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological	18s 28s acridine b23 c23 devised exposing fibrillarin gv homogenous hp1alpha impoverished isothiocyanate nlb nlbs nobox nsn nucleolar nucleoli nucleolin nucleolus nucleophosmin oocytes rrnas sc35 storing surrounded ubf unequivocally
Tagcloud (Intersection) ?