PRTFDC1 and FLAD1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		PRTFDC1	FLAD1
Description		phosphoribosyl transferase domain containing 1	flavin adenine dinucleotide synthetase 1
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GO Annotations	Cellular Component	Cytosol	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity Metal Ion Binding	Nucleotide Binding Catalytic Activity FMN Adenylyltransferase Activity Protein Binding ATP Binding Transferase Activity Nucleotidyltransferase Activity Identical Protein Binding FAD Diphosphatase Activity
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process	FAD Biosynthetic Process Riboflavin Metabolic Process Flavin Adenine Dinucleotide Biosynthetic Process
Pathways			Vitamin B2 (riboflavin) metabolism
Drugs
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Diisocyanate-induced asthma ( 25918132) Eosinophil count ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Intraocular pressure ( 29617998) Lymphocyte count ( 27863252 32888494) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 27863252 32888494) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 27863252 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 27863252 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		19 interacting genes: - CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 SPG21 STAT5A TCL1A TMEM14B VWA5A	21 interacting genes: ANXA7 APTX CDKN1A CLVS2 COPS3 CRABP2 DNM2 FXR1 GEMIN4 GRB7 L3MBTL3 NIF3L1 NUDT21 PRTFDC1 RCC1 REL SDCBP SMN1 TCF4 TK1 TRIM23
Entrez ID		56952	80308
HPRD ID		17917	17887
Ensembl ID		ENSG00000099256	ENSG00000160688
Uniprot IDs		Q9NRG1	Q8NFF5
PDB IDs		2JBH	8ROM 8RON
Enriched GO Terms of Interacting Partners?			Nucleus Identical Protein Binding SMN Complex Gemini Of Cajal Bodies Cytoplasm Cellular Component Assembly SMN-Sm Protein Complex Protein-containing Complex Assembly MRNA 3'-UTR AU-rich Region Binding Mitotic Cell Cycle Phase Transition Regulation Of Cell Growth Nuclear Body Cyclin Binding Cell Cycle Phase Transition Protein Sequestering Activity Protein Heterodimerization Activity Lipid Binding Protein-containing Complex Organization Interleukin-5 Receptor Complex Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Binding Positive Regulation Of Pro-B Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Nucleoside Metabolic Process
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