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PRTFDC1 and MCMBP
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PRTFDC1
MCMBP
Gene Name
phosphoribosyl transferase domain containing 1
minichromosome maintenance complex binding protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Plasma Membrane
MCM Complex
Molecular Function
Nucleotide Binding
Magnesium Ion Binding
Hypoxanthine Phosphoribosyltransferase Activity
Protein Homodimerization Activity
Chromatin Binding
Protein Binding
Biological Process
Purine Ribonucleoside Salvage
Adenine Salvage
Guanine Salvage
GMP Salvage
IMP Salvage
GMP Catabolic Process
Hypoxanthine Metabolic Process
DNA-dependent DNA Replication
Sister Chromatid Cohesion
Mitotic Nuclear Division
Cell Division
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
12 interactors:
DTNB
EEF2KMT
EPM2AIP1
EWSR1
FLAD1
GNPDA1
HPRT1
LGALS9B
MCMBP
NIF3L1
STAT5A
TCL1A
4 interactors:
DDIT3
MCM7
PRTFDC1
USP7
Entrez ID
56952
79892
HPRD ID
17917
07624
Ensembl ID
ENSG00000099256
ENSG00000197771
Uniprot IDs
Q9NRG1
Q9BTE3
PDB IDs
2JBH
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Mast Cell Differentiation
GMP Salvage
GMP Catabolic Process
Guanine Salvage
Glucosamine Catabolic Process
FAD Biosynthetic Process
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Regulation Of Mast Cell Differentiation
Adenine Salvage
Dihydrobiopterin Metabolic Process
Hypoxanthine Salvage
Development Of Secondary Male Sexual Characteristics
Positive Regulation Of Dopamine Metabolic Process
Hypoxanthine Metabolic Process
Hypoxanthine Biosynthetic Process
Negative Regulation Of Mast Cell Apoptotic Process
GMP Biosynthetic Process
Positive Regulation Of Glycogen (starch) Synthase Activity
Creatinine Metabolic Process
Regulation Of Mast Cell Apoptotic Process
Purine Nucleoside Monophosphate Catabolic Process
Glucosamine Metabolic Process
Positive Regulation Of Mast Cell Proliferation
Riboflavin Metabolic Process
Isoleucine Metabolic Process
Allantoin Metabolic Process
Purine Ribonucleoside Salvage
Taurine Metabolic Process
Positive Regulation Of Gamma-delta T Cell Differentiation
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Response To Organonitrogen Compound
Heterocycle Metabolic Process
Negative Regulation Of Erythrocyte Differentiation
Prolactin Signaling Pathway
GMP Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Positive Regulation Of Gamma-delta T Cell Activation
Development Of Secondary Female Sexual Characteristics
Valine Metabolic Process
Creatine Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Natural Killer Cell Differentiation
Succinate Metabolic Process
Regulation Of Glycogen (starch) Synthase Activity
Regulation Of Gamma-delta T Cell Differentiation
Development Of Secondary Sexual Characteristics
Purine Ribonucleoside Catabolic Process
Luteinization
Positive Regulation Of Glycogen Biosynthetic Process
Cellular Response To DNA Damage Stimulus
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Determination Of Dorsal Identity
Regulation Of Transcription Involved In Anterior/posterior Axis Specification
Cellular Response To Stress
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Maintenance Of DNA Methylation
ER Overload Response
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
MRNA Transcription From RNA Polymerase II Promoter
DNA Unwinding Involved In DNA Replication
Proteolysis Involved In Cellular Protein Catabolic Process
Blood Vessel Maturation
Cellular Protein Catabolic Process
MRNA Transcription
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Histone Deubiquitination
Negative Regulation Of Myoblast Differentiation
Cellular Response To Epidermal Growth Factor Stimulus
Response To Stress
Response To Epidermal Growth Factor
DNA Strand Elongation Involved In DNA Replication
Cellular Macromolecule Catabolic Process
DNA Strand Elongation
Positive Regulation Of Interleukin-8 Production
DNA Replication Initiation
Release Of Sequestered Calcium Ion Into Cytosol
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Regulation Of Sequestering Of Calcium Ion
Transcription-coupled Nucleotide-excision Repair
Regulation Of Myoblast Differentiation
Chromosome Organization
Negative Regulation Of Muscle Cell Differentiation
Cell Cycle Process
Calcium Ion Transport Into Cytosol
Cytosolic Calcium Ion Transport
DNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Positive Regulation Of Nuclease Activity
Regulation Of DNA-templated Transcription In Response To Stress
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of NF-kappaB Transcription Factor Activity
Heterocycle Metabolic Process
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