PRTFDC1 and LGALS9B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PRTFDC1	LGALS9B
Description		phosphoribosyl transferase domain containing 1	galectin 9B
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytosol
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding Galactoside Binding Carbohydrate Binding
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process	Positive Regulation Of Gene Expression Negative Regulation Of Type II Interferon Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Diisocyanate-induced asthma ( 25918132) Eosinophil count ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Intraocular pressure ( 29617998) Lymphocyte count ( 27863252 32888494) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 27863252 32888494) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 27863252 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 27863252 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494)
Interacting Genes		19 interacting genes: - CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 SPG21 STAT5A TCL1A TMEM14B VWA5A	8 interacting genes: ABI2 ATPAF2 DAB1 LONRF1 NTAQ1 PRTFDC1 QARS1 WWP2
Entrez ID		56952	284194
HPRD ID		17917	18932
Ensembl ID		ENSG00000099256	ENSG00000170298
Uniprot IDs		Q9NRG1	Q3B8N2
PDB IDs		2JBH
Enriched GO Terms of Interacting Partners?			Cerebellum Structural Organization Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Signaling Adaptor Activity Cytosol Glutamine-tRNA Ligase Activity Glutaminyl-tRNA Aminoacylation Zonula Adherens Assembly Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Lateral Motor Column Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Spinal Cord Motor Neuron Migration Neuron Migration
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