FLAD1 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FLAD1	ANXA7
Gene Name		flavin adenine dinucleotide synthetase 1	annexin A7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Cytosol Plasma Membrane	Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	FMN Adenylyltransferase Activity ATP Binding	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	FAD Biosynthetic Process Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Riboflavin Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Small Molecule Metabolic Process	Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Vitamin B2 (riboflavin) metabolism Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Metabolism of water-soluble vitamins and cofactors Defective MUT causes methylmalonic aciduria mut type Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		13 interactors: ANXA7 CDKN1A GEMIN4 GRB7 NUDT21 PRTFDC1 RCC1 REL SDCBP SMN1 TCF4 TK1 TRIM23	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		80308	310
HPRD ID		17887	01720
Ensembl ID		ENSG00000160688	ENSG00000138279
Uniprot IDs		Q8NFF5	B2R657 P20073
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Digestive Tract Development Digestive System Development Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecular Complex Assembly Spliceosomal SnRNP Assembly Negative Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Fetal Process Involved In Parturition RNA Splicing Skeletal Muscle Cell Proliferation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition MRNA Processing Protein Tetramerization Response To Extracellular Stimulus Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Cellular Component Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Maintenance Of DNA Repeat Elements MRNA Metabolic Process Cell Cycle Arrest Intestinal Epithelial Cell Maturation RNA Processing Positive Regulation Of Signal Transduction Response To Glucocorticoid G1/S Transition Of Mitotic Cell Cycle Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Response To Cortisol Thymidine Metabolic Process Embryonic Hindgut Morphogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Corticosteroid Small GTPase Mediated Signal Transduction Embryonic Genitalia Morphogenesis Response To Toxic Substance Positive Regulation Of Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Cellular Response To UV-B Myoblast Fate Commitment Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Ran GTPase Activity Tube Development Secretory Granule Localization Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?			annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?			annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?