PRTFDC1 and EPM2AIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRTFDC1	EPM2AIP1
Gene Name		phosphoribosyl transferase domain containing 1	EPM2A (laforin) interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Endoplasmic Reticulum
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Homodimerization Activity
	Biological Process	Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage GMP Salvage IMP Salvage GMP Catabolic Process Hypoxanthine Metabolic Process	Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 STAT5A TCL1A	16 interactors: ACTN1 C1orf50 CCNB1IP1 CPSF7 EMP2 EPM2A FHL3 KCTD1 MEOX2 PRTFDC1 REL SERPINF1 TNFAIP1 TRIM54 VPS52 ZBTB14
Entrez ID		56952	9852
HPRD ID		17917	07445
Ensembl ID		ENSG00000099256	ENSG00000178567
Uniprot IDs		Q9NRG1	Q7L775
PDB IDs		2JBH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Glucosamine Catabolic Process FAD Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Mast Cell Differentiation Adenine Salvage Dihydrobiopterin Metabolic Process Hypoxanthine Salvage Development Of Secondary Male Sexual Characteristics Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Negative Regulation Of Mast Cell Apoptotic Process GMP Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity Creatinine Metabolic Process Regulation Of Mast Cell Apoptotic Process Purine Nucleoside Monophosphate Catabolic Process Glucosamine Metabolic Process Positive Regulation Of Mast Cell Proliferation Riboflavin Metabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Purine Ribonucleoside Salvage Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Response To Organonitrogen Compound Heterocycle Metabolic Process Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway GMP Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Valine Metabolic Process Creatine Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Regulation Of Glycogen (starch) Synthase Activity Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Purine Ribonucleoside Catabolic Process Luteinization Positive Regulation Of Glycogen Biosynthetic Process	Actin Cytoskeleton Organization Multicellular Organismal Development Cellular Component Assembly Actin Filament-based Process Actin Filament Bundle Assembly Actin Filament Organization Developmental Process Cellular Response To Cobalt Ion Embryonic Ectodermal Digestive Tract Development Regulation Of Endothelial Cell Migration Habituation Protein Oligomerization Cellular Macromolecule Biosynthetic Process Protein Localization To Tight Junction Macromolecule Biosynthetic Process
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