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FLAD1
Gene Name
flavin adenine dinucleotide synthetase 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mitochondrial Matrix
Cytosol
Plasma Membrane
Molecular Function
FMN Adenylyltransferase Activity
ATP Binding
Biological Process
FAD Biosynthetic Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Riboflavin Metabolic Process
Mo-molybdopterin Cofactor Biosynthetic Process
Small Molecule Metabolic Process
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Vitamin B2 (riboflavin) metabolism
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Metabolism of water-soluble vitamins and cofactors
Defective MUT causes methylmalonic aciduria mut type
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in vitamin and cofactor metabolism
Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-protein Interactions
13 interactors:
ANXA7
CDKN1A
GEMIN4
GRB7
NUDT21
PRTFDC1
RCC1
REL
SDCBP
SMN1
TCF4
TK1
TRIM23
Entrez ID
80308
HPRD ID
17887
Ensembl ID
ENSG00000160688
Uniprot IDs
Q8NFF5
PDB IDs
Enriched GO Terms of Interacting Partners
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Cellular Component Assembly
Digestive Tract Development
Digestive System Development
Ribonucleoprotein Complex Assembly
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Cellular Macromolecular Complex Assembly
Spliceosomal SnRNP Assembly
Negative Regulation Of Gene Expression
Ribonucleoprotein Complex Biogenesis
Fetal Process Involved In Parturition
RNA Splicing
Skeletal Muscle Cell Proliferation
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
MRNA Processing
Protein Tetramerization
Response To Extracellular Stimulus
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Maintenance Of DNA Repeat Elements
MRNA Metabolic Process
Cell Cycle Arrest
Intestinal Epithelial Cell Maturation
RNA Processing
Positive Regulation Of Signal Transduction
Response To Glucocorticoid
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Extracellular Vesicular Exosome Assembly
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Response To Cortisol
Thymidine Metabolic Process
Embryonic Hindgut Morphogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Corticosteroid
Small GTPase Mediated Signal Transduction
Embryonic Genitalia Morphogenesis
Response To Toxic Substance
Positive Regulation Of Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Cellular Response To UV-B
Myoblast Fate Commitment
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Ran GTPase Activity
Tube Development
Secretory Granule Localization
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
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