FLAD1 and RCC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		FLAD1	RCC1
Description		flavin adenine dinucleotide synthetase 1	regulator of chromosome condensation 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Protein-containing Complex
	Molecular Function	Nucleotide Binding Catalytic Activity FMN Adenylyltransferase Activity Protein Binding ATP Binding Transferase Activity Nucleotidyltransferase Activity Identical Protein Binding FAD Diphosphatase Activity	DNA Binding Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	FAD Biosynthetic Process Riboflavin Metabolic Process Flavin Adenine Dinucleotide Biosynthetic Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Membrane Reassembly Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Viral Process Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly
Pathways		Vitamin B2 (riboflavin) metabolism	Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732) Red blood cell count ( 32888494) Refractive error ( 32231278)	Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		21 interacting genes: ANXA7 APTX CDKN1A CLVS2 COPS3 CRABP2 DNM2 FXR1 GEMIN4 GRB7 L3MBTL3 NIF3L1 NUDT21 PRTFDC1 RCC1 REL SDCBP SMN1 TCF4 TK1 TRIM23	50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CEBPA CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 LRIF1 NGFR NTMT1 NUDT21 NUP98 OGT PDHB PKM PTMA RAN RANBP1 RANBP3 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		80308	1104
HPRD ID		17887	01559
Ensembl ID		ENSG00000160688	ENSG00000180198
Uniprot IDs		Q8NFF5	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs		8ROM 8RON	1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB 8UX1
Enriched GO Terms of Interacting Partners?		Nucleus Identical Protein Binding SMN Complex Gemini Of Cajal Bodies Cytoplasm Cellular Component Assembly SMN-Sm Protein Complex Protein-containing Complex Assembly MRNA 3'-UTR AU-rich Region Binding Mitotic Cell Cycle Phase Transition Regulation Of Cell Growth Nuclear Body Cyclin Binding Cell Cycle Phase Transition Protein Sequestering Activity Protein Heterodimerization Activity Lipid Binding Protein-containing Complex Organization Interleukin-5 Receptor Complex Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Binding Positive Regulation Of Pro-B Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Nucleoside Metabolic Process	Chromatin Organization Nucleoplasm Nucleus Chromatin Remodeling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Structural Constituent Of Chromatin Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleosome Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Kinetochore Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Protein Heterodimerization Activity Nuclear Transport Nucleocytoplasmic Transport Nuclear Pore Protein Export From Nucleus Ribosomal Large Subunit Export From Nucleus Chromosome Positive Regulation Of DNA Metabolic Process Ribosomal Small Subunit Export From Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of DNA Replication Cytosol Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Nuclear Envelope Ribosomal Subunit Export From Nucleus Extracellular Exosome Nuclear Export Nuclear Export Signal Receptor Activity Protein Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteolysis TORC1 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Biosynthetic Process Nuclear Retinoic Acid Receptor Binding Pyruvate Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus MRNA Cleavage And Polyadenylation Specificity Factor Complex
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