RNF17 and UBE2U

Number of citations of the paper that reports this interaction (PubMedID 19690564)
61

Data Source:
BioGRID (two hybrid)

		RNF17	UBE2U
Description		ring finger protein 17	ubiquitin conjugating enzyme E2 U
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm	HULC Complex
	Molecular Function	Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding Protein Binding ATP Binding Transferase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Spermatogenesis Spermatid Development Cell Differentiation	Protein Polyubiquitination DNA Repair Protein Ubiquitination Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Severe bacterial meningitis ( 31092817)
Interacting Genes		2 interacting genes: RNF10 UBE2U	69 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF213 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2
Entrez ID		56163	148581
HPRD ID		05779	14599
Ensembl ID		ENSG00000132972	ENSG00000177414
Uniprot IDs		B7Z7S1 Q9BXT8	A0A0A0MRP4 A0A140VJY9 Q5VVX9
PDB IDs		2EQK	1YRV
Enriched GO Terms of Interacting Partners?		Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Proteasomal Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Extrinsic Component Of Postsynaptic Density Membrane HULC Complex Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation Ubiquitin-like Protein Transferase Activity Post-translational Protein Modification Macromolecule Catabolic Process Ubiquitin Conjugating Enzyme Activity Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Proteolysis Regulation Of Myelination Postsynaptic Signal Transduction Protein Monoubiquitination Protein Autoubiquitination Protein Modification Process Transferase Activity Cytosolic Ribosome Regulation Of Gliogenesis Catabolic Process Regulation Of Nervous System Process Negative Regulation Of Neurogenesis Negative Regulation Of Nervous System Development	Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Protein Ubiquitination Post-translational Protein Modification Zinc Ion Binding Protein Modification Process Ubiquitin-protein Transferase Activity Metal Ion Binding Transferase Activity Protein Metabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Macromolecule Metabolic Process Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Proteolysis Suppression Of Viral Release By Host Protein Autoubiquitination Catabolic Process Transcription Coactivator Activity Protein K63-linked Ubiquitination Innate Immune Response Protein Catabolic Process Proteasomal Protein Catabolic Process Defense Response To Symbiont Defense Response To Other Organism Response To Other Organism Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process SUMO Transferase Activity Response To Stress Response To External Biotic Stimulus Immune System Process Protein Sumoylation Immune Response Defense Response Defense Response To Virus Protein K48-linked Ubiquitination PRC1 Complex Regulation Of Type I Interferon Production Cytoplasm Regulation Of Viral Process Positive Regulation Of Catabolic Process Response To Virus PcG Protein Complex Ubiquitin Ligase Complex Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Negative Regulation Of Viral Process SnoRNA Splicing
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?