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VPS35 and ZNF512B
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
VPS35
ZNF512B
Gene Name
vacuolar protein sorting 35 homolog (S. cerevisiae)
zinc finger protein 512B
Image
Gene Ontology Annotations
Cellular Component
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Cytosol
Retromer Complex
Extracellular Vesicular Exosome
Tubular Endosome
Nucleus
Molecular Function
Protein Binding
Protein Transporter Activity
DNA Binding
Metal Ion Binding
Biological Process
Intracellular Protein Transport
Retrograde Transport, Endosome To Golgi
Transcytosis
Negative Regulation Of Late Endosome To Lysosome Transport
Retrograde Transport, Endosome To Plasma Membrane
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974
Signaling by Wnt
Signaling by WNT in cancer
WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
9 interactors:
APP
FAM21C
MTNR1B
SNX1
SNX3
VEGFA
VPS26B
VPS29
ZNF512B
60 interactors:
ANKLE2
ANKRD28
AP1G1
APLP2
ATRX
BRD1
BTBD2
CDC123
CREBZF
CTBP2
DCTN1
DDX3X
DROSHA
DVL3
EHMT2
FAM129B
FHL3
GLRX3
HEYL
HTATSF1
IL36RN
INVS
KDM2A
KDM3B
KLF10
KMT2B
L1TD1
LAMB2
LZTS2
MBD1
MYH10
OS9
PAPPA2
PBRM1
PDE4DIP
PEG10
PIAS4
PLCG2
PPP1R15A
PTPRF
RPS27A
SDF4
SIAH1
SMAD1
SPTBN1
SUPT5H
TGM2
TNKS2
TOM1
TOX4
TRAF1
TRAF4
VHL
VPS35
VPS41
VWF
XPC
XRCC6
YES1
ZMYM2
Entrez ID
55737
57473
HPRD ID
06085
13840
Ensembl ID
ENSG00000196700
Uniprot IDs
Q96QK1
Q96KM6
PDB IDs
2R17
2GQJ
Enriched GO Terms of Interacting Partners
?
Retrograde Transport, Endosome To Golgi
Vesicle-mediated Transport
Endosomal Transport
Establishment Of Localization In Cell
Cellular Localization
Intracellular Transport
Retrograde Transport, Endosome To Plasma Membrane
Regulation Of Cell Development
Platelet Degranulation
Positive Regulation Of Protein Kinase D Signaling
Basophil Chemotaxis
Intralumenal Vesicle Formation
Transport
Positive Regulation Of Protein Localization To Early Endosome
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Barbed-end Actin Filament Capping
Negative Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Retinal Ganglion Cell Axon Guidance
Coronary Vein Morphogenesis
Primitive Erythrocyte Differentiation
VEGF-activated Neuropilin Signaling Pathway
Regulation Of Receptor Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Peptidyl-tyrosine Autophosphorylation
Regulation Of Barbed-end Actin Filament Capping
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Histone Deacetylase Activity
Protein Transport
Cell Maturation
Establishment Of Protein Localization
Positive Regulation Of Lymphangiogenesis
Cardiac Vascular Smooth Muscle Cell Development
Positive Regulation Of Mast Cell Chemotaxis
Regulation Of Retinal Ganglion Cell Axon Guidance
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Cell Differentiation
Lamellipodium Morphogenesis
Collateral Sprouting
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
Axon Midline Choice Point Recognition
Regulation Of Histone Deacetylase Activity
Regulation Of Neurogenesis
Regulation Of Endocytosis
Positive Regulation Of Deacetylase Activity
Coronary Artery Morphogenesis
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Platelet Activation
Regulation Of Cell-substrate Adhesion
Regulation Of Cellular Process
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organ Development
System Development
Transcription, DNA-templated
Developmental Process
Chromosome Organization
Anatomical Structure Development
Regulation Of Gene Expression
RNA Biosynthetic Process
Response To Stimulus
Negative Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Modification
Negative Regulation Of Biosynthetic Process
Cell Cycle
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cell Cycle Process
Multicellular Organismal Development
Viral Genome Replication
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Organization
Wnt Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Cell Surface Receptor Signaling Pathway
Organelle Organization
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Chromatin Remodeling
RNA Metabolic Process
Primary MiRNA Processing
Vesicle-mediated Transport
Endosomal Transport
Regulation Of Signal Transduction
Cellular Response To Stress
Mitotic Cell Cycle Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Gene Expression
Response To Stress
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud
?
allosteric
biophysical
cargo
consists
deciphered
disrupts
endosomal
endosomes
fret
golgi
gtpase
hela
insights
instrumental
nexins
perturbed
rab7
recognizing
recruit
recruitment
recruits
recycle
retromer
snx
sorting
sub
vacuolar
vps26
Tagcloud (Difference)
?
allosteric
biophysical
cargo
consists
deciphered
disrupts
endosomal
endosomes
fret
golgi
gtpase
hela
insights
instrumental
nexins
perturbed
rab7
recognizing
recruit
recruitment
recruits
recycle
retromer
snx
sorting
sub
vacuolar
vps26
Tagcloud (Intersection)
?