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VPS35
Gene Name
vacuolar protein sorting 35 homolog (S. cerevisiae)
Image
Gene Ontology Annotations
Cellular Component
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Cytosol
Retromer Complex
Extracellular Vesicular Exosome
Tubular Endosome
Molecular Function
Protein Binding
Protein Transporter Activity
Biological Process
Intracellular Protein Transport
Retrograde Transport, Endosome To Golgi
Transcytosis
Negative Regulation Of Late Endosome To Lysosome Transport
Retrograde Transport, Endosome To Plasma Membrane
Pathways
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974
Signaling by Wnt
Signaling by WNT in cancer
WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
APP
FAM21C
MTNR1B
SNX1
SNX3
VEGFA
VPS26B
VPS29
ZNF512B
Entrez ID
55737
HPRD ID
06085
Ensembl ID
Uniprot IDs
Q96QK1
PDB IDs
2R17
Enriched GO Terms of Interacting Partners
?
Retrograde Transport, Endosome To Golgi
Vesicle-mediated Transport
Endosomal Transport
Establishment Of Localization In Cell
Cellular Localization
Intracellular Transport
Retrograde Transport, Endosome To Plasma Membrane
Regulation Of Cell Development
Platelet Degranulation
Positive Regulation Of Protein Kinase D Signaling
Basophil Chemotaxis
Intralumenal Vesicle Formation
Transport
Positive Regulation Of Protein Localization To Early Endosome
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Barbed-end Actin Filament Capping
Negative Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Retinal Ganglion Cell Axon Guidance
Coronary Vein Morphogenesis
Primitive Erythrocyte Differentiation
VEGF-activated Neuropilin Signaling Pathway
Regulation Of Receptor Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Peptidyl-tyrosine Autophosphorylation
Regulation Of Barbed-end Actin Filament Capping
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Histone Deacetylase Activity
Protein Transport
Cell Maturation
Establishment Of Protein Localization
Positive Regulation Of Lymphangiogenesis
Cardiac Vascular Smooth Muscle Cell Development
Positive Regulation Of Mast Cell Chemotaxis
Regulation Of Retinal Ganglion Cell Axon Guidance
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Cell Differentiation
Lamellipodium Morphogenesis
Collateral Sprouting
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
Axon Midline Choice Point Recognition
Regulation Of Histone Deacetylase Activity
Regulation Of Neurogenesis
Regulation Of Endocytosis
Positive Regulation Of Deacetylase Activity
Coronary Artery Morphogenesis
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Platelet Activation
Regulation Of Cell-substrate Adhesion
Tagcloud
?
allosteric
biophysical
cargo
consists
deciphered
disrupts
endosomal
endosomes
fret
golgi
gtpase
hela
insights
instrumental
nexins
perturbed
rab7
recognizing
recruit
recruitment
recruits
recycle
retromer
snx
sorting
sub
vacuolar
vps26