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ZNF446 and DGCR6
Number of citations of the paper that reports this interaction (PMID
24722188
)
1
Data Source:
BioGRID
(two hybrid)
ZNF446
DGCR6
Gene Name
zinc finger protein 446
DiGeorge syndrome critical region gene 6
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleus
Proteinaceous Extracellular Matrix
Nucleus
Molecular Function
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
DNA Binding
Metal Ion Binding
Molecular_function
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Cell Adhesion
Organ Morphogenesis
Pathways
Generic Transcription Pathway
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
25 interactors:
ACTN2
DGCR6
DGCR6L
FHL5
KRT40
KRTAP10-3
LZTS2
NOTCH2NL
PGBD1
PIN1
SUFU
TRIM27
ZKSCAN7
ZNF165
ZNF232
ZNF24
ZNF263
ZNF396
ZNF397
ZNF496
ZSCAN16
ZSCAN21
ZSCAN22
ZSCAN32
ZSCAN9
61 interactors:
ADAMTSL4
AES
AGTRAP
APP
ARNT2
C1orf94
C3orf62
CBLL1
CCDC33
CCDC36
CCDC67
CTAGE5
CTBP1
DLGAP2
DLX2
DNPEP
DOCK8
EFEMP2
EFHC2
ENKD1
FBF1
GOLGA2
GSE1
HGS
HOMEZ
IKZF3
KIAA1377
KLHL12
LZTS2
MBIP
MEIS2
MEOX2
MID2
MIPOL1
NAB2
NECAB2
NOTCH2NL
NQO2
NUP54
NUP62
PDLIM7
PRDM14
RABGEF1
REL
RFX6
RIMBP3
SPERT
SPRY2
SS18L1
TCF12
TCF4
TFIP11
TRAF1
TRAF2
TRIM27
TUBGCP4
VCP
ZBED1
ZC4H2
ZNF398
ZNF446
Entrez ID
55663
8214
HPRD ID
07934
03177
Ensembl ID
ENSG00000083838
ENSG00000183628
Uniprot IDs
Q9NWS9
Q14129
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
RNA Metabolic Process
Regulation Of Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transmembrane Transport
Negative Regulation Of Interleukin-2 Secretion
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Ion Transport
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Protein Localization
Negative Regulation Of Transport
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Negative Regulation Of Calcium Ion Import
Microspike Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Protein Localization To Cell Surface
Interferon-gamma Secretion
Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cellular Metabolic Process
Spindle Midzone Assembly
Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
RNA Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Gene Expression
Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Protein Binding
Regulation Of ERBB Signaling Pathway
Negative Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Cell Death
Developmental Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Signal Transduction
Regulation Of Signaling
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Protein Ubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Binding
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Modification By Small Protein Conjugation
Nitrogen Compound Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Tagcloud
?
1rn
antidopaminergic
daao
darpp
dgcr2
drd2
drd3
dtnbp1
evolves
facets
forcefully
g72
gabra1
gabra6
gabrp
gria1
grin1
grm3
merge
mglu2
networking
prodh
rgs4
slc1a2
slc1a6
underpinned
unifying
vulnerablility
zdhhc8
Tagcloud (Difference)
?
1rn
antidopaminergic
daao
darpp
dgcr2
drd2
drd3
dtnbp1
evolves
facets
forcefully
g72
gabra1
gabra6
gabrp
gria1
grin1
grm3
merge
mglu2
networking
prodh
rgs4
slc1a2
slc1a6
underpinned
unifying
vulnerablility
zdhhc8
Tagcloud (Intersection)
?