ZNF446 and ZNF263

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNF446	ZNF263
Gene Name		zinc finger protein 446	zinc finger protein 263
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway	Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ACTN2 DGCR6 DGCR6L FHL5 KRT40 KRTAP10-3 LZTS2 NOTCH2NL PGBD1 PIN1 SUFU TRIM27 ZKSCAN7 ZNF165 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF496 ZSCAN16 ZSCAN21 ZSCAN22 ZSCAN32 ZSCAN9	15 interactors: CLK2 CLK3 DVL2 EFEMP2 GPATCH2L NME7 PCBD1 PLEKHF2 SCAND1 SPG21 SUFU TCAF1 TRIM41 ZNF446 ZSCAN1
Entrez ID		55663	10127
HPRD ID		07934	05008
Ensembl ID		ENSG00000083838	ENSG00000006194
Uniprot IDs		Q9NWS9	D3DUC1 O14978
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression RNA Metabolic Process Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Ion Transport Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization Negative Regulation Of Transport Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Calcium Ion Import Microspike Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Protein Localization To Cell Surface Interferon-gamma Secretion Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity	Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of RNA Splicing Regulation Of Gene Expression Neural Tube Closure Regulation Of Nitrogen Compound Metabolic Process Convergent Extension Involved In Neural Plate Elongation Determination Of Left/right Symmetry Determination Of Bilateral Symmetry Regulation Of Embryonic Development Smoothened Signaling Pathway Pattern Specification Process Neural Tube Formation Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Embryonic Epithelial Tube Formation Epithelial Tube Formation Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Convergent Extension Involved In Organogenesis Tube Formation Morphogenesis Of Embryonic Epithelium Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Neural Plate Morphogenesis Neural Tube Development Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Tetrahydrobiopterin Biosynthetic Process Transcription, DNA-templated Protein Autophosphorylation
Tagcloud ?			affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous smarcc2 spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 zp2 zranb2
Tagcloud (Difference) ?			affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous smarcc2 spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 zp2 zranb2
Tagcloud (Intersection) ?