ZNF446 and ZNF232

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		ZNF446	ZNF232
Gene Name		zinc finger protein 446	zinc finger protein 232
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus	Nucleus
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ACTN2 DGCR6 DGCR6L FHL5 KRT40 KRTAP10-3 LZTS2 NOTCH2NL PGBD1 PIN1 SUFU TRIM27 ZKSCAN7 ZNF165 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF496 ZSCAN16 ZSCAN21 ZSCAN22 ZSCAN32 ZSCAN9	6 interactors: EMD MTUS2 NR2E3 PPCDC YY1 ZNF446
Entrez ID		55663	7775
HPRD ID		07934	15755
Ensembl ID		ENSG00000083838	ENSG00000167840
Uniprot IDs		Q9NWS9	I3L4J6 Q9UNY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression RNA Metabolic Process Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Ion Transport Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization Negative Regulation Of Transport Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Calcium Ion Import Microspike Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Protein Localization To Cell Surface Interferon-gamma Secretion Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity	Response To Prostaglandin F Eye Morphogenesis Transcription From RNA Polymerase II Promoter Positive Regulation Of Rhodopsin Gene Expression Regulation Of Rhodopsin Gene Expression Mitotic Nuclear Envelope Reassembly Response To Light Stimulus Response To UV-C Negative Regulation Of Catenin Import Into Nucleus Camera-type Eye Development Nuclear Envelope Reassembly Pantothenate Metabolic Process Eye Development Positive Regulation Of Protein Export From Nucleus Response To Radiation Coenzyme A Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Catenin Import Into Nucleus Coenzyme A Metabolic Process Nucleobase-containing Compound Metabolic Process Sensory Organ Development Regulation Of Protein Export From Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Mitotic Nuclear Envelope Disassembly Negative Regulation Of Cell Proliferation Negative Regulation Of Fibroblast Proliferation Transcription, DNA-templated Eye Photoreceptor Cell Development Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nuclear Envelope Disassembly Photoreceptor Cell Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Photoreceptor Cell Differentiation Response To Organic Substance
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