ZNF446 and ZNF24

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		ZNF446	ZNF24
Gene Name		zinc finger protein 446	zinc finger protein 24
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus	Nucleus Nucleoplasm
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Myelination Negative Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ACTN2 DGCR6 DGCR6L FHL5 KRT40 KRTAP10-3 LZTS2 NOTCH2NL PGBD1 PIN1 SUFU TRIM27 ZKSCAN7 ZNF165 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF496 ZSCAN16 ZSCAN21 ZSCAN22 ZSCAN32 ZSCAN9	40 interactors: APLP1 C14orf1 CCDC130 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G FANCA HAP1 HMGB1 KAT5 KIAA1377 LMO2 LRIF1 MID2 MZF1 PGBD1 PPP1CC RBM48 SCAND1 SEC62 SETDB1 SUMO1 TCAF1 TP53 TRIM25 UNC119 UTP14A ZBTB16 ZKSCAN8 ZNF165 ZNF174 ZNF396 ZNF446 ZNF483 ZNHIT3 ZSCAN21 ZSCAN32
Entrez ID		55663	7572
HPRD ID		07934	01921
Ensembl ID		ENSG00000083838	ENSG00000172466
Uniprot IDs		Q9NWS9	P17028
PDB IDs			1X6E 3LHR
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression RNA Metabolic Process Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Ion Transport Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization Negative Regulation Of Transport Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Calcium Ion Import Microspike Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Protein Localization To Cell Surface Interferon-gamma Secretion Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity	Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Base-excision Repair Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Viral Release From Host Cell DNA Repair Negative Regulation Of Viral Entry Into Host Cell Metabolic Process Regulation Of Viral Entry Into Host Cell Entrainment Of Circadian Clock By Photoperiod Regulation Of Viral Release From Host Cell Photoperiodism Entrainment Of Circadian Clock Protein Localization To Organelle Double-strand Break Repair Negative Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Negative Regulation Of Apoptotic Cell Clearance Cellular Response To DNA Damage Stimulus Cellular Response To Organic Substance Regulation Of Cellular Process
Tagcloud ?			18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf271 znf396 znf397
Tagcloud (Difference) ?			18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf271 znf396 znf397
Tagcloud (Intersection) ?